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CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.
Tai YT, Landesman Y, Acharya C, Calle Y, Zhong MY, Cea M, Tannenbaum D, Cagnetta A, Reagan M, Munshi AA, Senapedis W, Saint-Martin JR, Kashyap T, Shacham S, Kauffman M, Gu Y, Wu L, Ghobrial I, Zhan F, Kung AL, Schey SA, Richardson P, Munshi NC, Anderson KC. Tai YT, et al. Among authors: gu y. Leukemia. 2014 Jan;28(1):155-65. doi: 10.1038/leu.2013.115. Epub 2013 Apr 16. Leukemia. 2014. PMID: 23588715 Free PMC article.
The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells.
Chen T, Meng Z, Gan Y, Wang X, Xu F, Gu Y, Xu X, Tang J, Zhou H, Zhang X, Gan X, Van Ness C, Xu G, Huang L, Zhang X, Fang Y, Wu J, Zheng S, Jin J, Huang W, Xu R. Chen T, et al. Among authors: gu y. Leukemia. 2013 Jul;27(7):1469-78. doi: 10.1038/leu.2013.8. Epub 2013 Jan 11. Leukemia. 2013. PMID: 23307033
Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia.
Sanchez-Aguilera A, Rattmann I, Drew DZ, Müller LU, Summey V, Lucas DM, Byrd JC, Croce CM, Gu Y, Cancelas JA, Johnston P, Moritz T, Williams DA. Sanchez-Aguilera A, et al. Among authors: gu y. Leukemia. 2010 Jan;24(1):97-104. doi: 10.1038/leu.2009.217. Epub 2009 Oct 22. Leukemia. 2010. PMID: 19847197 Free PMC article.
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