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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. Yang JY, et al. Among authors: yamaguchi h. Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20. Nat Cell Biol. 2008. PMID: 18204439 Free PMC article.
A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.
Xie X, Hsu JL, Choi MG, Xia W, Yamaguchi H, Chen CT, Trinh BQ, Lu Z, Ueno NT, Wolf JK, Bast RC Jr, Hung MC. Xie X, et al. Among authors: yamaguchi h. Mol Cancer Ther. 2009 Aug;8(8):2375-82. doi: 10.1158/1535-7163.MCT-09-0056. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671744 Free PMC article.
FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization.
Su JL, Cheng X, Yamaguchi H, Chang YW, Hou CF, Lee DF, Ko HW, Hua KT, Wang YN, Hsiao M, Chen PB, Hsu JM, Bast RC Jr, Hortobagyi GN, Hung MC. Su JL, et al. Among authors: yamaguchi h. Cancer Res. 2011 Nov 1;71(21):6878-87. doi: 10.1158/0008-5472.CAN-11-0295. Epub 2011 Sep 12. Cancer Res. 2011. PMID: 21911455 Free PMC article.
Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1.
Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL, Chao CH, Yamaguchi H, Yang NK, Ding Q, Wang Y, Lai YJ, LaBaff AM, Wu TJ, Lin BR, Yang MH, Hortobagyi GN, Hung MC. Li CW, et al. Among authors: yamaguchi h. Cancer Res. 2012 Mar 1;72(5):1290-300. doi: 10.1158/0008-5472.CAN-11-3123. Epub 2012 Jan 17. Cancer Res. 2012. PMID: 22253230 Free PMC article.
4,911 results