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Synthesis of damaged DNA containing the oxidative lesion 3'-oxothymidine.
Bioorg Med Chem. 2017 Oct 15;25(20):5598-5602. doi: 10.1016/j.bmc.2017.08.032. Epub 2017 Sep 1.
Bioorg Med Chem. 2017.
PMID: 28927804
Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking.
Audat SA, Al-Shar'i NA, Al-Oudat BA, Bryant-Friedrich A, Bedi MF, Zayed AL, Al-Balas QA.
Audat SA, et al. Among authors: bedi mf.
Molecules. 2020 Jun 22;25(12):2871. doi: 10.3390/molecules25122871.
Molecules. 2020.
PMID: 32580506
Free PMC article.
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Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents.
Al-Oudat BA, Jaradat HM, Al-Balas QA, Al-Shar'i NA, Bryant-Friedrich A, Bedi MF.
Al-Oudat BA, et al. Among authors: bedi mf.
Bioorg Med Chem. 2020 Aug 15;28(16):115608. doi: 10.1016/j.bmc.2020.115608. Epub 2020 Jul 4.
Bioorg Med Chem. 2020.
PMID: 32690268
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Lead optimization and biological evaluation of diazenylbenzenesulfonamides inhibitors against glyoxalase-I enzyme as potential anticancer agents.
Al-Oudat BA, Al-Shar'i NA, Al-Balas QA, Audat SA, Alqudah MAY, Hamzah AH, Hallak RW, Bedi M, Bryant-Friedrich A.
Al-Oudat BA, et al.
Bioorg Chem. 2022 Mar;120:105657. doi: 10.1016/j.bioorg.2022.105657. Epub 2022 Feb 5.
Bioorg Chem. 2022.
PMID: 35152183
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AI is a viable alternative to high throughput screening: a 318-target study.
Atomwise AIMS Program.
Atomwise AIMS Program.
Sci Rep. 2024 Apr 2;14(1):7526. doi: 10.1038/s41598-024-54655-z.
Sci Rep. 2024.
PMID: 38565852
Free PMC article.
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Novel Chrysin-De-Allyl PAC-1 Hybrid Analogues as Anticancer Compounds: Design, Synthesis, and Biological Evaluation.
Al-Oudat BA, Ramapuram H, Malla S, Audat SA, Hussein N, Len JM, Kumari S, Bedi MF, Ashby CR Jr, Tiwari AK.
Al-Oudat BA, et al. Among authors: bedi mf.
Molecules. 2020 Jul 4;25(13):3063. doi: 10.3390/molecules25133063.
Molecules. 2020.
PMID: 32635530
Free PMC article.
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