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The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O. Krasemann S, et al. Among authors: madore c. Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008. Immunity. 2017. PMID: 28930663 Free PMC article.
The brain parenchyma has a type I interferon response that can limit virus spread.
Drokhlyansky E, Göz Aytürk D, Soh TK, Chrenek R, O'Loughlin E, Madore C, Butovsky O, Cepko CL. Drokhlyansky E, et al. Among authors: madore c. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E95-E104. doi: 10.1073/pnas.1618157114. Epub 2016 Dec 15. Proc Natl Acad Sci U S A. 2017. PMID: 27980033 Free PMC article.
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
Mazaheri F, Snaidero N, Kleinberger G, Madore C, Daria A, Werner G, Krasemann S, Capell A, Trümbach D, Wurst W, Brunner B, Bultmann S, Tahirovic S, Kerschensteiner M, Misgeld T, Butovsky O, Haass C. Mazaheri F, et al. Among authors: madore c. EMBO Rep. 2017 Jul;18(7):1186-1198. doi: 10.15252/embr.201743922. Epub 2017 May 8. EMBO Rep. 2017. PMID: 28483841 Free PMC article.
Microglial confetti party.
Madore C, Baufeld C, Butovsky O. Madore C, et al. Nat Neurosci. 2017 May 25;20(6):762-763. doi: 10.1038/nn.4570. Nat Neurosci. 2017. PMID: 28542157 Free PMC article.
Microglial Phenotypes and Functions in Multiple Sclerosis.
O'Loughlin E, Madore C, Lassmann H, Butovsky O. O'Loughlin E, et al. Among authors: madore c. Cold Spring Harb Perspect Med. 2018 Feb 1;8(2):a028993. doi: 10.1101/cshperspect.a028993. Cold Spring Harb Perspect Med. 2018. PMID: 29419406 Free PMC article. Review.
TREMendous 2 Be Social.
Calcagno N, Baufeld C, Madore C, Butovsky O. Calcagno N, et al. Among authors: madore c. Immunity. 2018 May 15;48(5):842-843. doi: 10.1016/j.immuni.2018.04.034. Immunity. 2018. PMID: 29768169 Free PMC article.
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia.
Hartmann K, Sepulveda-Falla D, Rose IVL, Madore C, Muth C, Matschke J, Butovsky O, Liddelow S, Glatzel M, Krasemann S. Hartmann K, et al. Among authors: madore c. Acta Neuropathol Commun. 2019 May 22;7(1):83. doi: 10.1186/s40478-019-0735-1. Acta Neuropathol Commun. 2019. PMID: 31118110 Free PMC article.
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