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PD-L1 is an activation-independent marker of brown adipocytes.
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL. Ingram JR, et al. Among authors: espinosa c. Nat Commun. 2017 Sep 21;8(1):647. doi: 10.1038/s41467-017-00799-8. Nat Commun. 2017. PMID: 28935898 Free PMC article.
Localized CD47 blockade enhances immunotherapy for murine melanoma.
Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M. Ingram JR, et al. Among authors: espinosa c. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10184-10189. doi: 10.1073/pnas.1710776114. Epub 2017 Sep 5. Proc Natl Acad Sci U S A. 2017. PMID: 28874561 Free PMC article.
Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M. Ingram JR, et al. Among authors: espinosa c. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3912-3917. doi: 10.1073/pnas.1801524115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581255 Free PMC article.
VoPo leverages cellular heterogeneity for predictive modeling of single-cell data.
Stanley N, Stelzer IA, Tsai AS, Fallahzadeh R, Ganio E, Becker M, Phongpreecha T, Nassar H, Ghaemi S, Maric I, Culos A, Chang AL, Xenochristou M, Han X, Espinosa C, Rumer K, Peterson L, Verdonk F, Gaudilliere D, Tsai E, Feyaerts D, Einhaus J, Ando K, Wong RJ, Obermoser G, Shaw GM, Stevenson DK, Angst MS, Gaudilliere B, Aghaeepour N. Stanley N, et al. Among authors: espinosa c. Nat Commun. 2020 Jul 27;11(1):3738. doi: 10.1038/s41467-020-17569-8. Nat Commun. 2020. PMID: 32719375 Free PMC article.
Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature.
Berson E, Sreenivas A, Phongpreecha T, Perna A, Grandi FC, Xue L, Ravindra NG, Payrovnaziri N, Mataraso S, Kim Y, Espinosa C, Chang AL, Becker M, Montine KS, Fox EJ, Chang HY, Corces MR, Aghaeepour N, Montine TJ. Berson E, et al. Among authors: espinosa c. Nat Commun. 2023 Aug 16;14(1):4947. doi: 10.1038/s41467-023-40611-4. Nat Commun. 2023. PMID: 37587197 Free PMC article.
Integration of mechanistic immunological knowledge into a machine learning pipeline improves predictions.
Culos A, Tsai AS, Stanley N, Becker M, Ghaemi MS, McIlwain DR, Fallahzadeh R, Tanada A, Nassar H, Espinosa C, Xenochristou M, Ganio E, Peterson L, Han X, Stelzer IA, Ando K, Gaudilliere D, Phongpreecha T, Marić I, Chang AL, Shaw GM, Stevenson DK, Bendall S, Davis KL, Fantl W, Nolan GP, Hastie T, Tibshirani R, Angst MS, Gaudilliere B, Aghaeepour N. Culos A, et al. Among authors: espinosa c. Nat Mach Intell. 2020 Oct;2(10):619-628. doi: 10.1038/s42256-020-00232-8. Epub 2020 Oct 12. Nat Mach Intell. 2020. PMID: 33294774 Free PMC article.
Multiomics Characterization of Preterm Birth in Low- and Middle-Income Countries.
Jehan F, Sazawal S, Baqui AH, Nisar MI, Dhingra U, Khanam R, Ilyas M, Dutta A, Mitra DK, Mehmood U, Deb S, Mahmud A, Hotwani A, Ali SM, Rahman S, Nizar A, Ame SM, Moin MI, Muhammad S, Chauhan A, Begum N, Khan W, Das S, Ahmed S, Hasan T, Khalid J, Rizvi SJR, Juma MH, Chowdhury NH, Kabir F, Aftab F, Quaiyum A, Manu A, Yoshida S, Bahl R, Rahman A, Pervin J, Winston J, Musonda P, Stringer JSA, Litch JA, Ghaemi MS, Moufarrej MN, Contrepois K, Chen S, Stelzer IA, Stanley N, Chang AL, Hammad GB, Wong RJ, Liu C, Quaintance CC, Culos A, Espinosa C, Xenochristou M, Becker M, Fallahzadeh R, Ganio E, Tsai AS, Gaudilliere D, Tsai ES, Han X, Ando K, Tingle M, Maric I, Wise PH, Winn VD, Druzin ML, Gibbs RS, Darmstadt GL, Murray JC, Shaw GM, Stevenson DK, Snyder MP, Quake SR, Angst MS, Gaudilliere B, Aghaeepour N; Alliance for Maternal and Newborn Health Improvement, the Global Alliance to Prevent Prematurity and Stillbirth, and the Prematurity Research Center at Stanford University. Jehan F, et al. Among authors: espinosa c. JAMA Netw Open. 2020 Dec 1;3(12):e2029655. doi: 10.1001/jamanetworkopen.2020.29655. JAMA Netw Open. 2020. PMID: 33337494 Free PMC article.
Data-Driven Modeling of Pregnancy-Related Complications.
Espinosa C, Becker M, Marić I, Wong RJ, Shaw GM, Gaudilliere B, Aghaeepour N, Stevenson DK; Prematurity Research Center at Stanford. Espinosa C, et al. Trends Mol Med. 2021 Aug;27(8):762-776. doi: 10.1016/j.molmed.2021.01.007. Epub 2021 Feb 8. Trends Mol Med. 2021. PMID: 33573911 Free PMC article. Review.
Objective Activity Parameters Track Patient-specific Physical Recovery Trajectories After Surgery and Link With Individual Preoperative Immune States.
Fallahzadeh R, Verdonk F, Ganio E, Culos A, Stanley N, Maric I, Chang AL, Becker M, Phongpreecha T, Xenochristou M, De Francesco D, Espinosa C, Gao X, Tsai A, Sultan P, Tingle M, Amanatullah DF, Huddleston JI, Goodman SB, Gaudilliere B, Angst MS, Aghaeepour N. Fallahzadeh R, et al. Among authors: espinosa c. Ann Surg. 2023 Mar 1;277(3):e503-e512. doi: 10.1097/SLA.0000000000005250. Epub 2021 Oct 8. Ann Surg. 2023. PMID: 35129529 Free PMC article.
A data-driven health index for neonatal morbidities.
De Francesco D, Blumenfeld YJ, Marić I, Mayo JA, Chang AL, Fallahzadeh R, Phongpreecha T, Butwick AJ, Xenochristou M, Phibbs CS, Bidoki NH, Becker M, Culos A, Espinosa C, Liu Q, Sylvester KG, Gaudilliere B, Angst MS, Stevenson DK, Shaw GM, Aghaeepour N. De Francesco D, et al. Among authors: espinosa c. iScience. 2022 Mar 22;25(4):104143. doi: 10.1016/j.isci.2022.104143. eCollection 2022 Apr 15. iScience. 2022. PMID: 35402862 Free PMC article.
257 results