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Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.
Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY. Mumbach MR, et al. Among authors: chang hy. Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25. Nat Genet. 2017. PMID: 28945252 Free PMC article.
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY. Gupta RA, et al. Among authors: chang hy. Nature. 2010 Apr 15;464(7291):1071-6. doi: 10.1038/nature08975. Nature. 2010. PMID: 20393566 Free PMC article.
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.
Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. Wang KC, et al. Among authors: chang hy. Nature. 2011 Apr 7;472(7341):120-4. doi: 10.1038/nature09819. Epub 2011 Mar 20. Nature. 2011. PMID: 21423168 Free PMC article.
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY. Hung T, et al. Among authors: chang hy. Nat Genet. 2011 Jun 5;43(7):621-9. doi: 10.1038/ng.848. Nat Genet. 2011. PMID: 21642992 Free PMC article.
Understanding the transcriptome through RNA structure.
Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Wan Y, et al. Among authors: chang hy. Nat Rev Genet. 2011 Aug 18;12(9):641-55. doi: 10.1038/nrg3049. Nat Rev Genet. 2011. PMID: 21850044 Free PMC article. Review.
Active chromatin and noncoding RNAs: an intimate relationship.
Flynn RA, Chang HY. Flynn RA, et al. Among authors: chang hy. Curr Opin Genet Dev. 2012 Apr;22(2):172-8. doi: 10.1016/j.gde.2011.11.002. Epub 2011 Dec 7. Curr Opin Genet Dev. 2012. PMID: 22154525 Free PMC article. Review.
Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts.
Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, Khavari PA. Lee CS, et al. Among authors: chang hy. Blood. 2012 Oct 18;120(16):3288-97. doi: 10.1182/blood-2012-04-423061. Epub 2012 Aug 30. Blood. 2012. PMID: 22936659 Free PMC article.
2,114 results