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Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy.
Hlaka L, Rosslee MJ, Ozturk M, Kumar S, Parihar SP, Brombacher F, Khalaf AI, Carter KC, Scott FJ, Suckling CJ, Guler R. Hlaka L, et al. Among authors: khalaf ai. J Antimicrob Chemother. 2017 Dec 1;72(12):3334-3341. doi: 10.1093/jac/dkx326. J Antimicrob Chemother. 2017. PMID: 28961913 Free PMC article.
Selective anti-malarial minor groove binders.
Scott FJ, Khalaf AI, Duffy S, Avery VM, Suckling CJ. Scott FJ, et al. Among authors: khalaf ai. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3326-3329. doi: 10.1016/j.bmcl.2016.05.039. Epub 2016 May 13. Bioorg Med Chem Lett. 2016. PMID: 27212070 Free article.
An evaluation of Minor Groove Binders as anti-lung cancer therapeutics.
Scott FJ, Puig-Sellart M, Khalaf AI, Henderson CJ, Westrop G, Watson DG, Carter K, Grant MH, Suckling CJ. Scott FJ, et al. Among authors: khalaf ai. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3478-86. doi: 10.1016/j.bmcl.2016.06.040. Epub 2016 Jun 16. Bioorg Med Chem Lett. 2016. PMID: 27349332 Free article.
An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.
Scott FJ, Nichol RJO, Khalaf AI, Giordani F, Gillingwater K, Ramu S, Elliott A, Zuegg J, Duffy P, Rosslee MJ, Hlaka L, Kumar S, Ozturk M, Brombacher F, Barrett M, Guler R, Suckling CJ. Scott FJ, et al. Among authors: khalaf ai. Eur J Med Chem. 2017 Aug 18;136:561-572. doi: 10.1016/j.ejmech.2017.05.039. Epub 2017 May 17. Eur J Med Chem. 2017. PMID: 28544982 Free article.
Selective in vitro anti-cancer activity of non-alkylating minor groove binders.
Nichol RJO, Khalaf AI, Sooda K, Hussain O, Griffiths HBS, Phillips R, Javid FA, Suckling CJ, Allison SJ, Scott FJ. Nichol RJO, et al. Among authors: khalaf ai. Medchemcomm. 2019 Jul 18;10(9):1620-1634. doi: 10.1039/c9md00268e. eCollection 2019 Sep 1. Medchemcomm. 2019. PMID: 32952999 Free PMC article.
39 results