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Single-cell transcriptional diversity is a hallmark of developmental potential.
Gulati GS, Sikandar SS, Wesche DJ, Manjunath A, Bharadwaj A, Berger MJ, Ilagan F, Kuo AH, Hsieh RW, Cai S, Zabala M, Scheeren FA, Lobo NA, Qian D, Yu FB, Dirbas FM, Clarke MF, Newman AM. Gulati GS, et al. Among authors: clarke mf. Science. 2020 Jan 24;367(6476):405-411. doi: 10.1126/science.aax0249. Science. 2020. PMID: 31974247 Free PMC article.
LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis.
Zabala M, Lobo NA, Antony J, Heitink LS, Gulati GS, Lam J, Parashurama N, Sanchez K, Adorno M, Sikandar SS, Kuo AH, Qian D, Kalisky T, Sim S, Li L, Dirbas FM, Somlo G, Newman A, Quake SR, Clarke MF. Zabala M, et al. Among authors: clarke mf. Cell Stem Cell. 2020 Aug 6;27(2):284-299.e8. doi: 10.1016/j.stem.2020.06.017. Epub 2020 Jul 20. Cell Stem Cell. 2020. PMID: 32693087 Free article.
Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model.
Reinitz F, Chen EY, Nicolis di Robilant B, Chuluun B, Antony J, Jones RC, Gubbi N, Lee K, Ho WHD, Kolluru SS, Qian D, Adorno M, Piltti K, Anderson A, Monje M, Heller HC, Quake SR, Clarke MF. Reinitz F, et al. Among authors: clarke mf. Elife. 2022 Mar 21;11:e66037. doi: 10.7554/eLife.66037. Elife. 2022. PMID: 35311644 Free PMC article.
Identification of a minority population of LMO2+ breast cancer cells that integrate into the vasculature and initiate metastasis.
Sikandar SS, Gulati GS, Antony J, Fetter I, Kuo AH, Ho WHD, Haro-Acosta V, Das S, Steen CB, Pereira TA, Qian D, Beachy PA, Dirbas FM, Red-Horse K, Rabbitts TH, Thiery JP, Newman AM, Clarke MF. Sikandar SS, et al. Among authors: clarke mf. Sci Adv. 2022 Nov 11;8(45):eabm3548. doi: 10.1126/sciadv.abm3548. Epub 2022 Nov 9. Sci Adv. 2022. PMID: 36351009 Free PMC article.
Quantitative assessment of single-cell RNA-sequencing methods.
Wu AR, Neff NF, Kalisky T, Dalerba P, Treutlein B, Rothenberg ME, Mburu FM, Mantalas GL, Sim S, Clarke MF, Quake SR. Wu AR, et al. Among authors: clarke mf. Nat Methods. 2014 Jan;11(1):41-6. doi: 10.1038/nmeth.2694. Epub 2013 Oct 20. Nat Methods. 2014. PMID: 24141493 Free PMC article.
175 results