Lynch M - Search Results

1

Catalytic properties of RNA polymerases IV and V: accuracy, nucleotide incorporation and rNTP/dNTP discrimination.

Marasco M, Li W, Lynch M, Pikaard CS. Marasco M, et al. Among authors: lynch m. Nucleic Acids Res. 2017 Nov 2;45(19):11315-11326. doi: 10.1093/nar/gkx794. Nucleic Acids Res. 2017. PMID: 28977461 Free PMC article.

2

The landscape of transcription errors in eukaryotic cells.

Gout JF, Li W, Fritsch C, Li A, Haroon S, Singh L, Hua D, Fazelinia H, Smith Z, Seeholzer S, Thomas K, Lynch M, Vermulst M. Gout JF, et al. Among authors: lynch m. Sci Adv. 2017 Oct 20;3(10):e1701484. doi: 10.1126/sciadv.1701484. eCollection 2017 Oct. Sci Adv. 2017. PMID: 29062891 Free PMC article.

3

Universally high transcript error rates in bacteria.

Li W, Lynch M. Li W, et al. Among authors: lynch m. Elife. 2020 May 29;9:e54898. doi: 10.7554/eLife.54898. Elife. 2020. PMID: 32469307 Free PMC article.

With errors identified from 9929 loci, the molecular spectrum and distribution of errors were uncovered in great detail. A GA substitution bias was observed in M. florum, which apparently has an error-prone RNA polymerase. ...This is because current methods for sequencing …

With errors identified from 9929 loci, the molecular spectrum and distribution of errors were uncovered in great detail. A GA substitution b …

4

Rates of Mutations and Transcript Errors in the Foodborne Pathogen Salmonella enterica subsp. enterica.

Pan J, Li W, Ni J, Wu K, Konigsberg I, Rivera CE, Tincher C, Gregory C, Zhou X, Doak TG, Lee H, Wang Y, Gao X, Lynch M, Long H. Pan J, et al. Among authors: lynch m. Mol Biol Evol. 2022 Apr 10;39(4):msac081. doi: 10.1093/molbev/msac081. Mol Biol Evol. 2022. PMID: 35446958 Free PMC article.

5

Simple evolutionary pathways to complex proteins.

Lynch M. Lynch M. Protein Sci. 2005 Sep;14(9):2217-25; discussion 2226-7. doi: 10.1110/ps.041171805. Protein Sci. 2005. PMID: 16131652 Free PMC article.

6

Evolutionary diversification of the Sm family of RNA-associated proteins.

Scofield DG, Lynch M. Scofield DG, et al. Among authors: lynch m. Mol Biol Evol. 2008 Nov;25(11):2255-67. doi: 10.1093/molbev/msn175. Epub 2008 Aug 7. Mol Biol Evol. 2008. PMID: 18687770 Free PMC article. Review.

7

Extraordinary genome stability in the ciliate Paramecium tetraurelia.

Sung W, Tucker AE, Doak TG, Choi E, Thomas WK, Lynch M. Sung W, et al. Among authors: lynch m. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19339-44. doi: 10.1073/pnas.1210663109. Epub 2012 Nov 5. Proc Natl Acad Sci U S A. 2012. PMID: 23129619 Free PMC article.

8

Genetics: Feedforward loop for diversity.

Lynch M. Lynch M. Nature. 2015 Jul 23;523(7561):414-6. doi: 10.1038/nature14634. Epub 2015 Jul 15. Nature. 2015. PMID: 26176917 Free PMC article.

9

The Spontaneous Mutation Rate in the Fission Yeast Schizosaccharomyces pombe.

Farlow A, Long H, Arnoux S, Sung W, Doak TG, Nordborg M, Lynch M. Farlow A, et al. Among authors: lynch m. Genetics. 2015 Oct;201(2):737-44. doi: 10.1534/genetics.115.177329. Epub 2015 Aug 10. Genetics. 2015. PMID: 26265703 Free PMC article.

10

Mutation pressure and the evolution of organelle genomic architecture.

Lynch M, Koskella B, Schaack S. Lynch M, et al. Science. 2006 Mar 24;311(5768):1727-30. doi: 10.1126/science.1118884. Science. 2006. PMID: 16556832 Review.

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