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Melphalan modifies the bone microenvironment by enhancing osteoclast formation.
Chai RC, McDonald MM, Terry RL, Kovačić N, Down JM, Pettitt JA, Mohanty ST, Shah S, Haffari G, Xu J, Gillespie MT, Rogers MJ, Price JT, Croucher PI, Quinn JMW. Chai RC, et al. Among authors: down jm. Oncotarget. 2017 Jul 10;8(40):68047-68058. doi: 10.18632/oncotarget.19152. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978095 Free PMC article.
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.
Lawson MA, McDonald MM, Kovacic N, Hua Khoo W, Terry RL, Down J, Kaplan W, Paton-Hough J, Fellows C, Pettitt JA, Neil Dear T, Van Valckenborgh E, Baldock PA, Rogers MJ, Eaton CL, Vanderkerken K, Pettit AR, Quinn JM, Zannettino AC, Phan TG, Croucher PI. Lawson MA, et al. Among authors: down j. Nat Commun. 2015 Dec 3;6:8983. doi: 10.1038/ncomms9983. Nat Commun. 2015. PMID: 26632274 Free PMC article.
Thyrostimulin Regulates Osteoblastic Bone Formation During Early Skeletal Development.
Bassett JH, van der Spek A, Logan JG, Gogakos A, Bagchi-Chakraborty J, Williams AJ, Murphy E, van Zeijl C, Down J, Croucher PI, Boyde A, Boelen A, Williams GR. Bassett JH, et al. Endocrinology. 2015 Sep;156(9):3098-113. doi: 10.1210/en.2014-1943. Epub 2015 May 27. Endocrinology. 2015. PMID: 26018249 Free PMC article.
Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer.
Junankar S, Shay G, Jurczyluk J, Ali N, Down J, Pocock N, Parker A, Nguyen A, Sun S, Kashemirov B, McKenna CE, Croucher PI, Swarbrick A, Weilbaecher K, Phan TG, Rogers MJ. Junankar S, et al. Cancer Discov. 2015 Jan;5(1):35-42. doi: 10.1158/2159-8290.CD-14-0621. Epub 2014 Oct 13. Cancer Discov. 2015. PMID: 25312016 Free PMC article.
Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche.
Müller LME, Migneco G, Scott GB, Down J, King S, Askar B, Jennings V, Oyajobi B, Scott K, West E, Ralph C, Samson A, Ilett EJ, Muthana M, Coffey M, Melcher A, Parrish C, Cook G, Lawson M, Errington-Mais F. Müller LME, et al. J Immunother Cancer. 2021 Mar;9(3):e001803. doi: 10.1136/jitc-2020-001803. J Immunother Cancer. 2021. PMID: 33741729 Free PMC article.
16 results