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A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability.
Davies B, Brown LA, Cais O, Watson J, Clayton AJ, Chang VT, Biggs D, Preece C, Hernandez-Pliego P, Krohn J, Bhomra A, Twigg SRF, Rimmer A, Kanapin A; WGS500 Consortium; Sen A, Zaiwalla Z, McVean G, Foster R, Donnelly P, Taylor JC, Blair E, Nutt D, Aricescu AR, Greger IH, Peirson SN, Flint J, Martin HC. Davies B, et al. Among authors: flint j. Hum Mol Genet. 2017 Oct 15;26(20):3869-3882. doi: 10.1093/hmg/ddx270. Hum Mol Genet. 2017. PMID: 29016847 Free PMC article.
Minisatellite mutational processes reduce F(st) estimates.
Flint J, Bond J, Rees DC, Boyce AJ, Roberts-Thomson JM, Excoffier L, Clegg JB, Beaumont MA, Nichols RA, Harding RM. Flint J, et al. Hum Genet. 1999 Dec;105(6):567-76. doi: 10.1007/s004399900185. Hum Genet. 1999. PMID: 10647891
Automatic analysis of agarose gel images.
Adiga PS, Bhomra A, Turri MG, Nicod A, Datta SR, Jeavons P, Mott R, Flint J. Adiga PS, et al. Among authors: flint j. Bioinformatics. 2001 Nov;17(11):1084-9. doi: 10.1093/bioinformatics/17.11.1084. Bioinformatics. 2001. PMID: 11724740
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
Solberg LC, Valdar W, Gauguier D, Nunez G, Taylor A, Burnett S, Arboledas-Hita C, Hernandez-Pliego P, Davidson S, Burns P, Bhattacharya S, Hough T, Higgs D, Klenerman P, Cookson WO, Zhang Y, Deacon RM, Rawlins JN, Mott R, Flint J. Solberg LC, et al. Among authors: flint j. Mamm Genome. 2006 Feb;17(2):129-46. doi: 10.1007/s00335-005-0112-1. Epub 2006 Feb 6. Mamm Genome. 2006. PMID: 16465593
A whole genome association study of neuroticism using DNA pooling.
Shifman S, Bhomra A, Smiley S, Wray NR, James MR, Martin NG, Hettema JM, An SS, Neale MC, van den Oord EJ, Kendler KS, Chen X, Boomsma DI, Middeldorp CM, Hottenga JJ, Slagboom PE, Flint J. Shifman S, et al. Among authors: flint j. Mol Psychiatry. 2008 Mar;13(3):302-12. doi: 10.1038/sj.mp.4002048. Epub 2007 Jul 31. Mol Psychiatry. 2008. PMID: 17667963 Free PMC article.
634 results