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Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.
Copping NA, Christian SGB, Ritter DJ, Islam MS, Buscher N, Zolkowska D, Pride MC, Berg EL, LaSalle JM, Ellegood J, Lerch JP, Reiter LT, Silverman JL, Dindot SV. Copping NA, et al. Among authors: christian sgb. Hum Mol Genet. 2017 Oct 15;26(20):3995-4010. doi: 10.1093/hmg/ddx289. Hum Mol Genet. 2017. PMID: 29016856 Free PMC article.
Genomic imprinting does not reduce the dosage of UBE3A in neurons.
Hillman PR, Christian SGB, Doan R, Cohen ND, Konganti K, Douglas K, Wang X, Samollow PB, Dindot SV. Hillman PR, et al. Among authors: christian sgb. Epigenetics Chromatin. 2017 May 15;10:27. doi: 10.1186/s13072-017-0134-4. eCollection 2017. Epigenetics Chromatin. 2017. PMID: 28515788 Free PMC article.
An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the UBE3A-AS transcript.
Dindot SV, Christian S, Murphy WJ, Berent A, Panagoulias J, Schlafer A, Ballard J, Radeva K, Robinson R, Myers L, Jepp T, Shaheen H, Hillman P, Konganti K, Hillhouse A, Bredemeyer KR, Black L, Douville J; FIRE consortium; FIRE Consortium. Dindot SV, et al. Sci Transl Med. 2023 Mar 22;15(688):eabf4077. doi: 10.1126/scitranslmed.abf4077. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947593
Immune response of human cultured cells towards macrocyclic Fe2PO and Fe2PC bioactive cyclophane complexes.
Salazar-Medina AJ, Velazquez-Contreras EF, Sugich-Miranda R, Santacruz H, Navarro RE, Rocha-Alonzo F, Islas-Osuna MA, Chen PL, Christian SGB, Romoser AA, Dindot SV, Sayes CM, Sotelo-Mundo RR, Criscitiello MF. Salazar-Medina AJ, et al. Among authors: christian sgb. PeerJ. 2020 Apr 20;8:e8956. doi: 10.7717/peerj.8956. eCollection 2020. PeerJ. 2020. PMID: 32341898 Free PMC article.