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Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.
Glia. 2018 Jan;66(1):191-205. doi: 10.1002/glia.23237. Epub 2017 Oct 11.
Glia. 2018.
PMID: 29024008
Distinct responses of human peripheral blood cells to different misfolded protein oligomers.
Leal-Lasarte M, Mannini B, Chiti F, Vendruscolo M, Dobson CM, Roodveldt C, Pozo D.
Leal-Lasarte M, et al.
Immunology. 2021 Oct;164(2):358-371. doi: 10.1111/imm.13377. Epub 2021 Jun 20.
Immunology. 2021.
PMID: 34043816
Free PMC article.
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MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS.
Pérez-Cabello JA, Silvera-Carrasco L, Franco JM, Capilla-González V, Armaos A, Gómez-Lima M, García-García R, Yap XW, Leal-Lasarte M, Lall D, Baloh RH, Martínez S, Miyata Y, Tartaglia GG, Sawarkar R, García-Domínguez M, Pozo D, Roodveldt C.
Pérez-Cabello JA, et al. Among authors: leal lasarte m.
Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302143120. doi: 10.1073/pnas.2302143120. Epub 2023 Jul 3.
Proc Natl Acad Sci U S A. 2023.
PMID: 37399380
Free PMC article.
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Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia.
Leal-Lasarte MM, Franco JM, Labrador-Garrido A, Pozo D, Roodveldt C.
Leal-Lasarte MM, et al.
FASEB J. 2017 Jul;31(7):2797-2816. doi: 10.1096/fj.201601163R. Epub 2017 Mar 23.
FASEB J. 2017.
PMID: 28336525
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