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Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities.
Li H, Sun W, Huang X, Lu X, Patel PR, Kim M, Orr MJ, Fisher RM, Tanaka TQ, McKew JC, Simeonov A, Sanderson PE, Zheng W, Williamson KC, Huang W. Li H, et al. Among authors: sanderson pe. ACS Comb Sci. 2017 Dec 11;19(12):748-754. doi: 10.1021/acscombsci.7b00119. Epub 2017 Oct 27. ACS Comb Sci. 2017. PMID: 29024590 Free PMC article.
Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIβ).
Krishnan K, Ziniel P, Li H, Huang X, Hupalo D, Gombakomba N, Guerrero SM, Dotrang T, Lu X, Caridha D, Sternberg AR, Hughes E, Sun W, Bargieri DY, Roepe PD, Sciotti RJ, Wilkerson MD, Dalgard CL, Tawa GJ, Wang AQ, Xu X, Zheng W, Sanderson PE, Huang W, Williamson KC. Krishnan K, et al. Among authors: sanderson pe. ACS Pharmacol Transl Sci. 2020 Sep 11;3(5):948-964. doi: 10.1021/acsptsci.0c00078. eCollection 2020 Oct 9. ACS Pharmacol Transl Sci. 2020. PMID: 33073193 Free PMC article.
Drug combination therapy increases successful drug repositioning.
Sun W, Sanderson PE, Zheng W. Sun W, et al. Among authors: sanderson pe. Drug Discov Today. 2016 Jul;21(7):1189-95. doi: 10.1016/j.drudis.2016.05.015. Epub 2016 May 27. Drug Discov Today. 2016. PMID: 27240777 Free PMC article. Review.
Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.
Shrimp JH, Janiszewski J, Chen CZ, Xu M, Wilson KM, Kales SC, Sanderson PE, Shinn P, Schneider R, Itkin Z, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zheng W, Simeonov A, Hall MD. Shrimp JH, et al. Among authors: sanderson pe. ACS Infect Dis. 2022 Jun 10;8(6):1191-1203. doi: 10.1021/acsinfecdis.2c00172. Epub 2022 Jun 1. ACS Infect Dis. 2022. PMID: 35648838 Free PMC article.
41 results