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Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity.
Bertels F, Marzel A, Leventhal G, Mitov V, Fellay J, Günthard HF, Böni J, Yerly S, Klimkait T, Aubert V, Battegay M, Rauch A, Cavassini M, Calmy A, Bernasconi E, Schmid P, Scherrer AU, Müller V, Bonhoeffer S, Kouyos R, Regoes RR; Swiss HIV Cohort Study. Bertels F, et al. Among authors: boni j. Mol Biol Evol. 2018 Jan 1;35(1):27-37. doi: 10.1093/molbev/msx246. Mol Biol Evol. 2018. PMID: 29029206 Free PMC article.
Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load.
Alizon S, von Wyl V, Stadler T, Kouyos RD, Yerly S, Hirschel B, Böni J, Shah C, Klimkait T, Furrer H, Rauch A, Vernazza PL, Bernasconi E, Battegay M, Bürgisser P, Telenti A, Günthard HF, Bonhoeffer S; Swiss HIV Cohort Study. Alizon S, et al. Among authors: boni j. PLoS Pathog. 2010 Sep 30;6(9):e1001123. doi: 10.1371/journal.ppat.1001123. PLoS Pathog. 2010. PMID: 20941398 Free PMC article.
Estimating the basic reproductive number from viral sequence data.
Stadler T, Kouyos R, von Wyl V, Yerly S, Böni J, Bürgisser P, Klimkait T, Joos B, Rieder P, Xie D, Günthard HF, Drummond AJ, Bonhoeffer S; Swiss HIV Cohort Study. Stadler T, et al. Among authors: boni j. Mol Biol Evol. 2012 Jan;29(1):347-57. doi: 10.1093/molbev/msr217. Epub 2011 Sep 2. Mol Biol Evol. 2012. PMID: 21890480
Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds.
Yang WL, Kouyos RD, Böni J, Yerly S, Klimkait T, Aubert V, Scherrer AU, Shilaih M, Hinkley T, Petropoulos C, Bonhoeffer S, Günthard HF; Swiss HIV Cohort Study (SHCS). Yang WL, et al. Among authors: boni j. PLoS Pathog. 2015 Mar 23;11(3):e1004722. doi: 10.1371/journal.ppat.1004722. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25798934 Free PMC article. Clinical Trial.
Genotypic Resistance Tests Sequences Reveal the Role of Marginalized Populations in HIV-1 Transmission in Switzerland.
Shilaih M, Marzel A, Yang WL, Scherrer AU, Schüpbach J, Böni J, Yerly S, Hirsch HH, Aubert V, Cavassini M, Klimkait T, Vernazza PL, Bernasconi E, Furrer H, Günthard HF, Kouyos R; Swiss HIV Cohort Study. Shilaih M, et al. Among authors: boni j. Sci Rep. 2016 Jun 14;6:27580. doi: 10.1038/srep27580. Sci Rep. 2016. PMID: 27297284 Free PMC article.
Determinants of HIV-1 broadly neutralizing antibody induction.
Rusert P, Kouyos RD, Kadelka C, Ebner H, Schanz M, Huber M, Braun DL, Hozé N, Scherrer A, Magnus C, Weber J, Uhr T, Cippa V, Thorball CW, Kuster H, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Fellay J, Regoes RR, Günthard HF, Trkola A; Swiss HIV Cohort Study. Rusert P, et al. Among authors: boni j. Nat Med. 2016 Nov;22(11):1260-1267. doi: 10.1038/nm.4187. Epub 2016 Sep 26. Nat Med. 2016. PMID: 27668936
Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART.
Wan C, Bachmann N, Mitov V, Blanquart F, Céspedes SP, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Walti L, Calmy A, Vernazza P, Bernasconi E, Cavassini M, Metzner KJ, Günthard HF, Kouyos RD; Swiss HIV Cohort Study. Wan C, et al. Among authors: boni j. Nat Commun. 2020 Nov 2;11(1):5542. doi: 10.1038/s41467-020-19198-7. Nat Commun. 2020. PMID: 33139735 Free PMC article.
A Phylogeny-aware GWAS Framework to Correct for Heritable Pathogen Effects on Infectious Disease Traits.
Nadeau S, Thorball CW, Kouyos R, Günthard HF, Böni J, Yerly S, Perreau M, Klimkait T, Rauch A, Hirsch HH, Cavassini M, Vernazza P, Bernasconi E, Fellay J, Mitov V, Stadler T; Swiss HIV Cohort Study (SHCS). Nadeau S, et al. Among authors: boni j. Mol Biol Evol. 2022 Aug 3;39(8):msac163. doi: 10.1093/molbev/msac163. Mol Biol Evol. 2022. PMID: 35921544 Free PMC article.
492 results