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Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.
Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z Jr, Gukovsky I, Gukovskaya AS. Biczo G, et al. Among authors: whitelegge j. Gastroenterology. 2018 Feb;154(3):689-703. doi: 10.1053/j.gastro.2017.10.012. Epub 2017 Oct 23. Gastroenterology. 2018. PMID: 29074451 Free PMC article.
Small lipidated anti-obesity compounds derived from neuromedin U.
Micewicz ED, Bahattab OS, Willars GB, Waring AJ, Navab M, Whitelegge JP, McBride WH, Ruchala P. Micewicz ED, et al. Among authors: whitelegge jp. Eur J Med Chem. 2015 Aug 28;101:616-26. doi: 10.1016/j.ejmech.2015.07.020. Epub 2015 Jul 14. Eur J Med Chem. 2015. PMID: 26204509 Free PMC article.
Lipid-conjugated Smac analogues.
Micewicz ED, Ratikan JA, Waring AJ, Whitelegge JP, McBride WH, Ruchala P. Micewicz ED, et al. Among authors: whitelegge jp. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4419-27. doi: 10.1016/j.bmcl.2015.09.017. Epub 2015 Sep 8. Bioorg Med Chem Lett. 2015. PMID: 26384289 Free PMC article.
Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model.
Waldron RT, Su HY, Piplani H, Capri J, Cohn W, Whitelegge JP, Faull KF, Sakkiah S, Abrol R, Yang W, Zhou B, Freeman MR, Pandol SJ, Lugea A. Waldron RT, et al. Among authors: whitelegge jp. Cell Mol Gastroenterol Hepatol. 2018 Jan 6;5(4):479-497. doi: 10.1016/j.jcmgh.2018.01.001. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 29930975 Free PMC article.
HSP70 Copurifies with Zika Virus Particles.
Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW. Khachatoorian R, et al. Virology. 2018 Sep;522:228-233. doi: 10.1016/j.virol.2018.07.009. Epub 2018 Jul 25. Virology. 2018. PMID: 30053656 Free article.
Uncovering the Mechanism of Aggregation of Human Transthyretin.
Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS. Saelices L, et al. Among authors: whitelegge j. J Biol Chem. 2015 Nov 27;290(48):28932-43. doi: 10.1074/jbc.M115.659912. Epub 2015 Oct 12. J Biol Chem. 2015. PMID: 26459562 Free PMC article.
4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.
Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. Micewicz ED, et al. Among authors: whitelegge jp. PLoS One. 2017 Jul 21;12(7):e0181577. doi: 10.1371/journal.pone.0181577. eCollection 2017. PLoS One. 2017. PMID: 28732024 Free PMC article.
281 results