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Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.
Fernandez-Ruiz D, Lau LS, Ghazanfari N, Jones CM, Ng WY, Davey GM, Berthold D, Holz L, Kato Y, Enders MH, Bayarsaikhan G, Hendriks SH, Lansink LIM, Engel JA, Soon MSF, James KR, Cozijnsen A, Mollard V, Uboldi AD, Tonkin CJ, de Koning-Ward TF, Gilson PR, Kaisho T, Haque A, Crabb BS, Carbone FR, McFadden GI, Heath WR. Fernandez-Ruiz D, et al. Among authors: cozijnsen a. J Immunol. 2017 Dec 15;199(12):4165-4179. doi: 10.4049/jimmunol.1700186. Epub 2017 Oct 30. J Immunol. 2017. PMID: 29084838 Free PMC article.
Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility.
Kan A, Tan YH, Angrisano F, Hanssen E, Rogers KL, Whitehead L, Mollard VP, Cozijnsen A, Delves MJ, Crawford S, Sinden RE, McFadden GI, Leckie C, Bailey J, Baum J. Kan A, et al. Among authors: cozijnsen a. Cell Microbiol. 2014 May;16(5):734-50. doi: 10.1111/cmi.12283. Epub 2014 Mar 28. Cell Microbiol. 2014. PMID: 24612056 Free PMC article.
CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria.
Lau LS, Fernandez-Ruiz D, Mollard V, Sturm A, Neller MA, Cozijnsen A, Gregory JL, Davey GM, Jones CM, Lin YH, Haque A, Engwerda CR, Nie CQ, Hansen DS, Murphy KM, Papenfuss AT, Miles JJ, Burrows SR, de Koning-Ward T, McFadden GI, Carbone FR, Crabb BS, Heath WR. Lau LS, et al. Among authors: cozijnsen a. PLoS Pathog. 2014 May 22;10(5):e1004135. doi: 10.1371/journal.ppat.1004135. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24854165 Free PMC article.
Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes.
Goodman CD, Siregar JE, Mollard V, Vega-Rodríguez J, Syafruddin D, Matsuoka H, Matsuzaki M, Toyama T, Sturm A, Cozijnsen A, Jacobs-Lorena M, Kita K, Marzuki S, McFadden GI. Goodman CD, et al. Among authors: cozijnsen a. Science. 2016 Apr 15;352(6283):349-53. doi: 10.1126/science.aad9279. Science. 2016. PMID: 27081071 Free PMC article.
Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.
Fernandez-Ruiz D, Ng WY, Holz LE, Ma JZ, Zaid A, Wong YC, Lau LS, Mollard V, Cozijnsen A, Collins N, Li J, Davey GM, Kato Y, Devi S, Skandari R, Pauley M, Manton JH, Godfrey DI, Braun A, Tay SS, Tan PS, Bowen DG, Koch-Nolte F, Rissiek B, Carbone FR, Crabb BS, Lahoud M, Cockburn IA, Mueller SN, Bertolino P, McFadden GI, Caminschi I, Heath WR. Fernandez-Ruiz D, et al. Among authors: cozijnsen a. Immunity. 2016 Oct 18;45(4):889-902. doi: 10.1016/j.immuni.2016.08.011. Epub 2016 Sep 27. Immunity. 2016. PMID: 27692609 Free article.
CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver.
Holz LE, Prier JE, Freestone D, Steiner TM, English K, Johnson DN, Mollard V, Cozijnsen A, Davey GM, Godfrey DI, Yui K, Mackay LK, Lahoud MH, Caminschi I, McFadden GI, Bertolino P, Fernandez-Ruiz D, Heath WR. Holz LE, et al. Among authors: cozijnsen a. Cell Rep. 2018 Oct 2;25(1):68-79.e4. doi: 10.1016/j.celrep.2018.08.094. Cell Rep. 2018. PMID: 30282039 Free article.
Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.
Fernandez-Ruiz D, Ng WY, Holz LE, Ma JZ, Zaid A, Wong YC, Lau LS, Mollard V, Cozijnsen A, Collins N, Li J, Davey GM, Kato Y, Devi S, Skandari R, Pauley M, Manton JH, Godfrey DI, Braun A, Tay SS, Tan PS, Bowen DG, Koch-Nolte F, Rissiek B, Carbone FR, Crabb BS, Lahoud M, Cockburn IA, Mueller SN, Bertolino P, McFadden GI, Caminschi I, Heath WR. Fernandez-Ruiz D, et al. Among authors: cozijnsen a. Immunity. 2019 Oct 15;51(4):780. doi: 10.1016/j.immuni.2019.09.019. Immunity. 2019. PMID: 31618655 Free article. No abstract available.
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice.
Valencia-Hernandez AM, Ng WY, Ghazanfari N, Ghilas S, de Menezes MN, Holz LE, Huang C, English K, Naung M, Tan PS, Tullett KM, Steiner TM, Enders MH, Beattie L, Chua YC, Jones CM, Cozijnsen A, Mollard V, Cai Y, Bowen DG, Purcell AW, La Gruta NL, Villadangos JA, de Koning-Ward T, Barry AE, Barchet W, Cockburn IA, McFadden GI, Gras S, Lahoud MH, Bertolino P, Schittenhelm RB, Caminschi I, Heath WR, Fernandez-Ruiz D. Valencia-Hernandez AM, et al. Among authors: cozijnsen a. Cell Host Microbe. 2020 Jun 10;27(6):950-962.e7. doi: 10.1016/j.chom.2020.04.010. Epub 2020 May 11. Cell Host Microbe. 2020. PMID: 32396839 Free article.
30 results