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Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.
Fernandez-Ruiz D, Lau LS, Ghazanfari N, Jones CM, Ng WY, Davey GM, Berthold D, Holz L, Kato Y, Enders MH, Bayarsaikhan G, Hendriks SH, Lansink LIM, Engel JA, Soon MSF, James KR, Cozijnsen A, Mollard V, Uboldi AD, Tonkin CJ, de Koning-Ward TF, Gilson PR, Kaisho T, Haque A, Crabb BS, Carbone FR, McFadden GI, Heath WR. Fernandez-Ruiz D, et al. Among authors: engel ja. J Immunol. 2017 Dec 15;199(12):4165-4179. doi: 10.4049/jimmunol.1700186. Epub 2017 Oct 30. J Immunol. 2017. PMID: 29084838 Free PMC article.
Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.
Akter J, Khoury DS, Aogo R, Lansink LIM, SheelaNair A, Thomas BS, Laohamonthonkul P, Pernold CPS, Dixon MWA, Soon MSF, Fogg LG, Engel JA, Elliott T, Sebina I, James KR, Cromer D, Davenport MP, Haque A. Akter J, et al. Among authors: engel ja. PLoS Pathog. 2019 Feb 27;15(2):e1007599. doi: 10.1371/journal.ppat.1007599. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30811498 Free PMC article.
Development of circulating CD4+ T-cell memory.
Soon MS, Engel JA, Lee HJ, Haque A. Soon MS, et al. Among authors: engel ja. Immunol Cell Biol. 2019 Aug;97(7):617-624. doi: 10.1111/imcb.12272. Epub 2019 Jun 5. Immunol Cell Biol. 2019. PMID: 31120158 Review.
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.
Ng SS, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, Kuns R, Chauhan SB, Hou J, Li XY, Frame TCM, McEnroe BA, Moore E, Na J, Engel JA, Soon MSF, Singh B, Kueh AJ, Herold MJ, Montes de Oca M, Singh SS, Bunn PT, Aguilera AR, Casey M, Braun M, Ghazanfari N, Wani S, Wang Y, Amante FH, Edwards CL, Haque A, Dougall WC, Singh OP, Baxter AG, Teng MWL, Loukas A, Daly NL, Cloonan N, Degli-Esposti MA, Uzonna J, Heath WR, Bald T, Tey SK, Nakamura K, Hill GR, Kumar R, Sundar S, Smyth MJ, Engwerda CR. Ng SS, et al. Among authors: engel ja. Nat Immunol. 2020 Oct;21(10):1205-1218. doi: 10.1038/s41590-020-0758-6. Epub 2020 Aug 24. Nat Immunol. 2020. PMID: 32839608 Free PMC article.
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory.
Soon MSF, Lee HJ, Engel JA, Straube J, Thomas BS, Pernold CPS, Clarke LS, Laohamonthonkul P, Haldar RN, Williams CG, Lansink LIM, Moreira ML, Bramhall M, Koufariotis LT, Wood S, Chen X, James KR, Lönnberg T, Lane SW, Belz GT, Engwerda CR, Khoury DS, Davenport MP, Svensson V, Teichmann SA, Haque A. Soon MSF, et al. Among authors: engel ja. Nat Immunol. 2020 Dec;21(12):1597-1610. doi: 10.1038/s41590-020-0800-8. Epub 2020 Oct 12. Nat Immunol. 2020. PMID: 33046889
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