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Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.
Fernandez-Ruiz D, Lau LS, Ghazanfari N, Jones CM, Ng WY, Davey GM, Berthold D, Holz L, Kato Y, Enders MH, Bayarsaikhan G, Hendriks SH, Lansink LIM, Engel JA, Soon MSF, James KR, Cozijnsen A, Mollard V, Uboldi AD, Tonkin CJ, de Koning-Ward TF, Gilson PR, Kaisho T, Haque A, Crabb BS, Carbone FR, McFadden GI, Heath WR. Fernandez-Ruiz D, et al. Among authors: lansink lim. J Immunol. 2017 Dec 15;199(12):4165-4179. doi: 10.4049/jimmunol.1700186. Epub 2017 Oct 30. J Immunol. 2017. PMID: 29084838 Free PMC article.
IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blood-Stage Plasmodium Infection.
James KR, Soon MSF, Sebina I, Fernandez-Ruiz D, Davey G, Liligeto UN, Nair AS, Fogg LG, Edwards CL, Best SE, Lansink LIM, Schroder K, Wilson JAC, Austin R, Suhrbier A, Lane SW, Hill GR, Engwerda CR, Heath WR, Haque A. James KR, et al. Among authors: lansink lim. J Immunol. 2018 Feb 15;200(4):1443-1456. doi: 10.4049/jimmunol.1700782. Epub 2018 Jan 10. J Immunol. 2018. PMID: 29321276
Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.
Akter J, Khoury DS, Aogo R, Lansink LIM, SheelaNair A, Thomas BS, Laohamonthonkul P, Pernold CPS, Dixon MWA, Soon MSF, Fogg LG, Engel JA, Elliott T, Sebina I, James KR, Cromer D, Davenport MP, Haque A. Akter J, et al. Among authors: lansink lim. PLoS Pathog. 2019 Feb 27;15(2):e1007599. doi: 10.1371/journal.ppat.1007599. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30811498 Free PMC article.
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory.
Soon MSF, Lee HJ, Engel JA, Straube J, Thomas BS, Pernold CPS, Clarke LS, Laohamonthonkul P, Haldar RN, Williams CG, Lansink LIM, Moreira ML, Bramhall M, Koufariotis LT, Wood S, Chen X, James KR, Lönnberg T, Lane SW, Belz GT, Engwerda CR, Khoury DS, Davenport MP, Svensson V, Teichmann SA, Haque A. Soon MSF, et al. Among authors: lansink lim. Nat Immunol. 2020 Dec;21(12):1597-1610. doi: 10.1038/s41590-020-0800-8. Epub 2020 Oct 12. Nat Immunol. 2020. PMID: 33046889
Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations.
Austin RJ, Straube J, Bruedigam C, Pali G, Jacquelin S, Vu T, Green J, Gräsel J, Lansink L, Cooper L, Lee SJ, Chen NT, Lee CW, Haque A, Heidel FH, D'Andrea R, Hill GR, Mullally A, Milsom MD, Bywater M, Lane SW. Austin RJ, et al. Leukemia. 2020 Apr;34(4):1075-1089. doi: 10.1038/s41375-019-0638-y. Epub 2019 Nov 15. Leukemia. 2020. PMID: 31732720 Free PMC article.
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites.
Lansink LIM, Skinner OP, Engel JA, Lee HJ, Soon MSF, Williams CG, SheelaNair A, Pernold CPS, Laohamonthonkul P, Akter J, Stoll T, Hill MM, Talman AM, Russell A, Lawniczak M, Jia X, Chua B, Anderson D, Creek DJ, Davenport MP, Khoury DS, Haque A. Lansink LIM, et al. mBio. 2023 Aug 31;14(4):e0112923. doi: 10.1128/mbio.01129-23. Epub 2023 Jul 14. mBio. 2023. PMID: 37449844 Free PMC article.