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Two independent modes of chromatin organization revealed by cohesin removal.
Schwarzer W, Abdennur N, Goloborodko A, Pekowska A, Fudenberg G, Loe-Mie Y, Fonseca NA, Huber W, Haering CH, Mirny L, Spitz F. Schwarzer W, et al. Among authors: haering ch. Nature. 2017 Nov 2;551(7678):51-56. doi: 10.1038/nature24281. Epub 2017 Sep 27. Nature. 2017. PMID: 29094699 Free PMC article.
The cohesin ring concatenates sister DNA molecules.
Haering CH, Farcas AM, Arumugam P, Metson J, Nasmyth K. Haering CH, et al. Nature. 2008 Jul 17;454(7202):297-301. doi: 10.1038/nature07098. Epub 2008 Jul 2. Nature. 2008. PMID: 18596691 Free article.
Cohesin in determining chromosome architecture.
Haering CH, Jessberger R. Haering CH, et al. Exp Cell Res. 2012 Jul 15;318(12):1386-93. doi: 10.1016/j.yexcr.2012.03.016. Epub 2012 Mar 24. Exp Cell Res. 2012. PMID: 22472347 Review.
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Lee BG, Merkel F, Allegretti M, Hassler M, Cawood C, Lecomte L, O'Reilly FJ, Sinn LR, Gutierrez-Escribano P, Kschonsak M, Bravo S, Nakane T, Rappsilber J, Aragon L, Beck M, Löwe J, Haering CH. Lee BG, et al. Among authors: haering ch. Nat Struct Mol Biol. 2020 Aug;27(8):743-751. doi: 10.1038/s41594-020-0457-x. Epub 2020 Jul 13. Nat Struct Mol Biol. 2020. PMID: 32661420 Free PMC article.
Chromosomal cohesin forms a ring.
Gruber S, Haering CH, Nasmyth K. Gruber S, et al. Among authors: haering ch. Cell. 2003 Mar 21;112(6):765-77. doi: 10.1016/s0092-8674(03)00162-4. Cell. 2003. PMID: 12654244 Free article.
53 results