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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies.
Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, Zhou Y, Nimer SD, Harbour JW, Wahlestedt C, Xu M, Yang FC. Yang H, et al. Among authors: chen z, chen s. Blood. 2018 Jan 18;131(3):328-341. doi: 10.1182/blood-2017-06-789669. Epub 2017 Nov 7. Blood. 2018. PMID: 29113963 Free PMC article.
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.
Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Li X, et al. Among authors: chen s. Blood. 2005 May 1;105(9):3465-71. doi: 10.1182/blood-2004-06-2483. Epub 2005 Jan 11. Blood. 2005. PMID: 15644418 Free PMC article.
Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model.
Rhodes SD, Wu X, He Y, Chen S, Yang H, Staser KW, Wang J, Zhang P, Jiang C, Yokota H, Dong R, Peng X, Yang X, Murthy S, Azhar M, Mohammad KS, Xu M, Guise TA, Yang FC. Rhodes SD, et al. Among authors: chen s. J Bone Miner Res. 2013 Dec;28(12):2476-89. doi: 10.1002/jbmr.1992. J Bone Miner Res. 2013. PMID: 23703870 Free PMC article.
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