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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies.
Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, Zhou Y, Nimer SD, Harbour JW, Wahlestedt C, Xu M, Yang FC. Yang H, et al. Among authors: wahlestedt c. Blood. 2018 Jan 18;131(3):328-341. doi: 10.1182/blood-2017-06-789669. Epub 2017 Nov 7. Blood. 2018. PMID: 29113963 Free PMC article.
Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.
Swords RT, Azzam D, Al-Ali H, Lohse I, Volmar CH, Watts JM, Perez A, Rodriguez A, Vargas F, Elias R, Vega F, Zelent A, Brothers SP, Abbasi T, Trent J, Rangwala S, Deutsch Y, Conneally E, Drusbosky L, Cogle CR, Wahlestedt C. Swords RT, et al. Among authors: wahlestedt c. Leuk Res. 2018 Jan;64:34-41. doi: 10.1016/j.leukres.2017.11.008. Epub 2017 Nov 11. Leuk Res. 2018. PMID: 29175379 Free PMC article. Clinical Trial.
Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins.
Sartor GC, Malvezzi AM, Kumar A, Andrade NS, Wiedner HJ, Vilca SJ, Janczura KJ, Bagheri A, Al-Ali H, Powell SK, Brown PT, Volmar CH, Foster TC, Zeier Z, Wahlestedt C. Sartor GC, et al. Among authors: wahlestedt c. J Neurosci. 2019 Jan 23;39(4):612-626. doi: 10.1523/JNEUROSCI.1604-18.2018. Epub 2018 Nov 30. J Neurosci. 2019. PMID: 30504275 Free PMC article.
Drug and disease signature integration identifies synergistic combinations in glioblastoma.
Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, Sarkaria JN, Subramanian A, Golub TR, Schürer SC, Ayad NG. Stathias V, et al. Among authors: wahlestedt c. Nat Commun. 2018 Dec 14;9(1):5315. doi: 10.1038/s41467-018-07659-z. Nat Commun. 2018. PMID: 30552330 Free PMC article.
BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT.
Copsel SN, Lightbourn CO, Barreras H, Lohse I, Wolf D, Bader CS, Manov J, Kale BJ, Shah D, Brothers SP, Perez VL, Komanduri KV, Wahlestedt C, Levy RB. Copsel SN, et al. Among authors: wahlestedt c. Front Immunol. 2019 Jan 24;9:3104. doi: 10.3389/fimmu.2018.03104. eCollection 2018. Front Immunol. 2019. PMID: 30733722 Free PMC article.
Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734.
Spriano F, Gaudio E, Cascione L, Tarantelli C, Melle F, Motta G, Priebe V, Rinaldi A, Golino G, Mensah AA, Aresu L, Zucca E, Pileri S, Witcher M, Brown B, Wahlestedt C, Giles F, Stathis A, Bertoni F. Spriano F, et al. Among authors: wahlestedt c. Blood Adv. 2020 Sep 8;4(17):4124-4135. doi: 10.1182/bloodadvances.2020001879. Blood Adv. 2020. PMID: 32882003 Free PMC article.
314 results