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Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).
J Med Chem. 2017 Nov 22;60(22):9184-9204. doi: 10.1021/acs.jmedchem.7b00941. Epub 2017 Nov 9.
J Med Chem. 2017.
PMID: 29120638
Free PMC article.
N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay.
Furuya T, Shapiro AB, Comita-Prevoir J, Kuenstner EJ, Zhang J, Ribe SD, Chen A, Hines D, Moussa SH, Carter NM, Sylvester MA, Romero JAC, Vega CV, Sacco MD, Chen Y, O'Donnell JP, Durand-Reville TF, Miller AA, Tommasi RA.
Furuya T, et al. Among authors: kuenstner ej.
Bioorg Med Chem. 2020 Dec 15;28(24):115826. doi: 10.1016/j.bmc.2020.115826. Epub 2020 Oct 28.
Bioorg Med Chem. 2020.
PMID: 33160146
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Synthesis of rearranged indole diterpenes of the paxilline type.
Schatz DJ, Kuenstner EJ, George DT, Pronin SV.
Schatz DJ, et al. Among authors: kuenstner ej.
Nat Prod Rep. 2022 May 26;39(5):946-968. doi: 10.1039/d1np00062d.
Nat Prod Rep. 2022.
PMID: 34931646
Free PMC article.
Review.
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Synthesis of isobemisiose, neosartose, and fischerose: three α-1,6-linked trehalose-based oligosaccharides identified from Neosartorya fischeri.
Kuenstner EJ, Palumbo EA, Levine J, Snyder NL.
Kuenstner EJ, et al.
RSC Adv. 2020 Jun 12;10(38):22726-22729. doi: 10.1039/d0ra04137h. eCollection 2020 Jun 10.
RSC Adv. 2020.
PMID: 35514568
Free PMC article.
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A Concise Approach to Paxilline Indole Diterpenes.
George DT, Kuenstner EJ, Pronin SV.
George DT, et al. Among authors: kuenstner ej.
J Am Chem Soc. 2015 Dec 16;137(49):15410-3. doi: 10.1021/jacs.5b11129. Epub 2015 Dec 7.
J Am Chem Soc. 2015.
PMID: 26593869
Free PMC article.
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Functionality and prevalence of trehalose-based oligosaccharides as novel compatible solutes in ascospores of Neosartorya fischeri (Aspergillus fischeri) and other fungi.
Wyatt TT, van Leeuwen MR, Golovina EA, Hoekstra FA, Kuenstner EJ, Palumbo EA, Snyder NL, Visagie C, Verkennis A, Hallsworth JE, Wösten HA, Dijksterhuis J.
Wyatt TT, et al. Among authors: kuenstner ej.
Environ Microbiol. 2015 Feb;17(2):395-411. doi: 10.1111/1462-2920.12558. Epub 2014 Oct 22.
Environ Microbiol. 2015.
PMID: 25040129
Free PMC article.
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