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Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
International Consortium on Lithium Genetics (ConLi+Gen); Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Étain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Ösby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P… See abstract for full author list ➔ International Consortium on Lithium Genetics (ConLi+Gen), et al. Among authors: hoffmann p. JAMA Psychiatry. 2018 Jan 1;75(1):65-74. doi: 10.1001/jamapsychiatry.2017.3433. JAMA Psychiatry. 2018. PMID: 29121268 Free PMC article. Clinical Trial.
Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility.
Li M, Wang Y, Zheng XB, Ikeda M, Iwata N, Luo XJ, Chong SA, Lee J, Rietschel M, Zhang F, Müller-Myhsok B, Cichon S, Weinberger DR, Mattheisen M, Schulze TG, Martin NG, Mitchell PB, Schofield PR, Liu JJ, Su B; MooDS Consortium. Li M, et al. Schizophr Res. 2012 Dec;142(1-3):200-5. doi: 10.1016/j.schres.2012.10.008. Epub 2012 Oct 25. Schizophr Res. 2012. PMID: 23102693
Genome-wide association study reveals two new risk loci for bipolar disorder.
Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Forstner AJ, Schumacher J, Breuer R, Meier S, Herms S, Hoffmann P, Lacour A, Witt SH, Reif A, Müller-Myhsok B, Lucae S, Maier W, Schwarz M, Vedder H, Kammerer-Ciernioch J, Pfennig A, Bauer M, Hautzinger M, Moebus S, Priebe L, Czerski PM, Hauser J, Lissowska J, Szeszenia-Dabrowska N, Brennan P, McKay JD, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, Krasnow V, Chuchalin A, Babadjanova G, Pantelejeva G, Abramova LI, Tiganov AS, Polonikov A, Khusnutdinova E, Alda M, Grof P, Rouleau GA, Turecki G, Laprise C, Rivas F, Mayoral F, Kogevinas M, Grigoroiu-Serbanescu M, Propping P, Becker T, Rietschel M, Nöthen MM, Cichon S. Mühleisen TW, et al. Among authors: hoffmann p. Nat Commun. 2014 Mar 11;5:3339. doi: 10.1038/ncomms4339. Nat Commun. 2014. PMID: 24618891 Free article.
Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway.
Al Chawa T, Ludwig KU, Fier H, Pötzsch B, Reich RH, Schmidt G, Braumann B, Daratsianos N, Böhmer AC, Schuencke H, Alblas M, Fricker N, Hoffmann P, Knapp M, Lange C, Nöthen MM, Mangold E. Al Chawa T, et al. Among authors: hoffmann p. Birth Defects Res A Clin Mol Teratol. 2014 Jun;100(6):493-8. doi: 10.1002/bdra.23244. Epub 2014 Apr 7. Birth Defects Res A Clin Mol Teratol. 2014. PMID: 24706492
A common microdeletion affecting a hippocampus- and amygdala-specific isoform of tryptophan hydroxylase 2 is not associated with affective disorders.
Hammer C, Degenhardt F, Priebe L, Stütz AM, Heilmann S, Waszak SM, Schlattl A, Mangold E, Hoffmann P, Nöthen MM, Rietschel M, Rappold G, Korbel J, Cichon S, Niesler B; MooDS Consortium. Hammer C, et al. Among authors: hoffmann p. Bipolar Disord. 2014 Nov;16(7):764-8. doi: 10.1111/bdi.12207. Epub 2014 Apr 23. Bipolar Disord. 2014. PMID: 24754353
Variant GADL1 and response to lithium in bipolar I disorder.
Consortium on Lithium Genetics; Hou L, Heilbronner U, Rietschel M, Kato T, Kuo PH, McMahon FJ, Schulze TG. Consortium on Lithium Genetics, et al. N Engl J Med. 2014 May 8;370(19):1857-9. doi: 10.1056/NEJMc1401817. N Engl J Med. 2014. PMID: 24806176 Free PMC article. No abstract available.
Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on the patients' clinical outcome.
Woltmann A, Chen B, Lascorz J, Johansson R, Eyfjörd JE, Hamann U, Manjer J, Enquist-Olsson K, Henriksson R, Herms S, Hoffmann P, Hemminki K, Lenner P, Försti A. Woltmann A, et al. Among authors: hoffmann p. PLoS One. 2014 Jun 2;9(6):e98229. doi: 10.1371/journal.pone.0098229. eCollection 2014. PLoS One. 2014. PMID: 24886783 Free PMC article.
Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia.
Forstner AJ, Basmanav FB, Mattheisen M, Böhmer AC, Hollegaard MV, Janson E, Strengman E, Priebe L, Degenhardt F, Hoffmann P, Herms S, Maier W, Mössner R, Rujescu D, Ophoff RA, Moebus S, Mortensen PB, Børglum AD, Hougaard DM, Frank J, Witt SH, Rietschel M, Zimmer A, Nöthen MM, Miró X, Cichon S. Forstner AJ, et al. Among authors: hoffmann p. J Psychiatry Neurosci. 2014 Nov;39(6):386-96. doi: 10.1503/jpn.130189. J Psychiatry Neurosci. 2014. PMID: 24936775 Free PMC article.
SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, Kornhuber J, Peters O, Naj AC, Chouraki V, Bellenguez C, Gerrish A; International Genomics of Alzheimer's Project (IGAP); Alzheimer's Disease Neuroimaging Initiative (ADNI); Heun R, Frölich L, Hüll M, Buscemi L, Herms S, Kölsch H, Scheltens P, Breteler MM, Rüther E, Wiltfang J, Goate A, Jessen F, Maier W, Heneka MT, Becker T, Nöthen MM. Ramirez A, et al. Among authors: hoffmann p. Hum Mol Genet. 2014 Dec 15;23(24):6644-58. doi: 10.1093/hmg/ddu372. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027320 Free PMC article.
1,657 results