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Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity of PfSPZ Vaccine for Malaria in Healthy Equatoguinean Men.
Olotu A, Urbano V, Hamad A, Eka M, Chemba M, Nyakarungu E, Raso J, Eburi E, Mandumbi DO, Hergott D, Maas CD, Ayekaba MO, Milang DN, Rivas MR, Schindler T, Embon OM, Ruben AJ, Saverino E, Abebe Y, Kc N, James ER, Murshedkar T, Manoj A, Chakravarty S, Li M, Adams M, Schwabe C, Segura JL, Daubenberger C, Tanner M, Richie TL, Billingsley PF, Lee Sim BK, Abdulla S, Hoffman SL. Olotu A, et al. Among authors: lee sim bk. Am J Trop Med Hyg. 2018 Jan;98(1):308-318. doi: 10.4269/ajtmh.17-0449. Epub 2018 Jan 1. Am J Trop Med Hyg. 2018. PMID: 29141739 Free PMC article. Clinical Trial.
Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon.
Lell B, Mordmüller B, Dejon Agobe JC, Honkpehedji J, Zinsou J, Mengue JB, Loembe MM, Adegnika AA, Held J, Lalremruata A, Nguyen TT, Esen M, Kc N, Ruben AJ, Chakravarty S, Lee Sim BK, Billingsley PF, James ER, Richie TL, Hoffman SL, Kremsner PG. Lell B, et al. Among authors: lee sim bk. Am J Trop Med Hyg. 2018 Feb;98(2):508-515. doi: 10.4269/ajtmh.17-0343. Epub 2017 Dec 14. Am J Trop Med Hyg. 2018. PMID: 29260650 Free PMC article.
Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies.
Zenklusen I, Jongo S, Abdulla S, Ramadhani K, Lee Sim BK, Cardamone H, Flannery EL, Nguyen T, Fishbaugher M, Steel RWJ, Betz W, Carmago N, Mikolajczak S, Kappe SHI, Hoffman SL, Sack BK, Daubenberger C. Zenklusen I, et al. Among authors: lee sim bk. J Infect Dis. 2018 Apr 23;217(10):1569-1578. doi: 10.1093/infdis/jiy080. J Infect Dis. 2018. PMID: 29438525 Free PMC article. Clinical Trial.
Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period.
Rothen J, Murie C, Carnes J, Anupama A, Abdulla S, Chemba M, Mpina M, Tanner M, Lee Sim BK, Hoffman SL, Gottardo R, Daubenberger C, Stuart K. Rothen J, et al. Among authors: lee sim bk. PLoS One. 2018 Jun 19;13(6):e0199392. doi: 10.1371/journal.pone.0199392. eCollection 2018. PLoS One. 2018. PMID: 29920562 Free PMC article.
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
McNamara HA, Idris AH, Sutton HJ, Vistein R, Flynn BJ, Cai Y, Wiehe K, Lyke KE, Chatterjee D, Kc N, Chakravarty S, Lee Sim BK, Hoffman SL, Bonsignori M, Seder RA, Cockburn IA. McNamara HA, et al. Among authors: lee sim bk. Cell Host Microbe. 2020 Oct 7;28(4):572-585.e7. doi: 10.1016/j.chom.2020.07.001. Epub 2020 Jul 21. Cell Host Microbe. 2020. PMID: 32697938 Free article.
Identification of the Glycan Binding Profile of Human and Rodent Plasmodium Sporozoites.
Poole J, Hartley-Tassell LE, Day CJ, Stanisic DI, Groves PL, Chakravarty S, Lee Sim BK, Hoffman SL, Tiralongo J, Bovin N, Doolan DL, Jennings MP. Poole J, et al. Among authors: lee sim bk. ACS Infect Dis. 2021 Aug 13;7(8):2383-2389. doi: 10.1021/acsinfecdis.1c00084. Epub 2021 Jun 25. ACS Infect Dis. 2021. PMID: 34170120