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Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia.
Zhu X, Zhou B, Pattni R, Gleason K, Tan C, Kalinowski A, Sloan S, Fiston-Lavier AS, Mariani J, Petrov D, Barres BA, Duncan L, Abyzov A, Vogel H; Brain Somatic Mosaicism Network; Moran JV, Vaccarino FM, Tamminga CA, Levinson DF, Urban AE. Zhu X, et al. Nat Neurosci. 2021 Feb;24(2):186-196. doi: 10.1038/s41593-020-00767-4. Epub 2021 Jan 11. Nat Neurosci. 2021. PMID: 33432196 Free PMC article.
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons.
Reid DA, Reed PJ, Schlachetzki JCM, Nitulescu II, Chou G, Tsui EC, Jones JR, Chandran S, Lu AT, McClain CA, Ooi JH, Wang TW, Lana AJ, Linker SB, Ricciardulli AS, Lau S, Schafer ST, Horvath S, Dixon JR, Hah N, Glass CK, Gage FH. Reid DA, et al. Among authors: linker sb. Science. 2021 Apr 2;372(6537):91-94. doi: 10.1126/science.abb9032. Science. 2021. PMID: 33795458 Free PMC article.
The role of retrotransposable elements in ageing and age-associated diseases.
Gorbunova V, Seluanov A, Mita P, McKerrow W, Fenyö D, Boeke JD, Linker SB, Gage FH, Kreiling JA, Petrashen AP, Woodham TA, Taylor JR, Helfand SL, Sedivy JM. Gorbunova V, et al. Among authors: linker sb. Nature. 2021 Aug;596(7870):43-53. doi: 10.1038/s41586-021-03542-y. Epub 2021 Aug 4. Nature. 2021. PMID: 34349292 Free PMC article. Review.
Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons.
Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, Fuertes FD, Scheuermann RH, Lee J, Lein ES, Schork N, McConnell MJ, Gage FH, Lasken RS. Krishnaswami SR, et al. Among authors: linker sb. Nat Protoc. 2016 Mar;11(3):499-524. doi: 10.1038/nprot.2016.015. Epub 2016 Feb 18. Nat Protoc. 2016. PMID: 26890679 Free PMC article.
Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJE, Parylak SL, Paquola ACM, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. Lacar B, et al. Among authors: linker sb. Nat Commun. 2016 Apr 19;7:11022. doi: 10.1038/ncomms11022. Nat Commun. 2016. PMID: 27090946 Free PMC article.
41 results