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CM-101: Type I Collagen-targeted MR Imaging Probe for Detection of Liver Fibrosis.
Farrar CT, Gale EM, Kennan R, Ramsay I, Masia R, Arora G, Looby K, Wei L, Kalpathy-Cramer J, Bunzel MM, Zhang C, Zhu Y, Akiyama TE, Klimas M, Pinto S, Diyabalanage H, Tanabe KK, Humblet V, Fuchs BC, Caravan P. Farrar CT, et al. Among authors: arora g. Radiology. 2018 May;287(2):581-589. doi: 10.1148/radiol.2017170595. Epub 2017 Nov 20. Radiology. 2018. PMID: 29156148 Free PMC article.
The farnesoid X receptor agonist EDP-305 reduces interstitial renal fibrosis in a mouse model of unilateral ureteral obstruction.
Li S, Ghoshal S, Sojoodi M, Arora G, Masia R, Erstad DJ, Ferriera DS, Li Y, Wang G, Lanuti M, Caravan P, Or YS, Jiang LJ, Tanabe KK, Fuchs BC. Li S, et al. Among authors: arora g. FASEB J. 2019 Jun;33(6):7103-7112. doi: 10.1096/fj.201801699R. Epub 2019 Mar 18. FASEB J. 2019. PMID: 30884252 Free PMC article.
YAP inhibition may be a novel antifibrotic mechanism of FXR agonism, and EDP-305 could be used to treat renal fibrosis.-Li, S., Ghoshal, S., Sojoodi, M., Arora, G., Masia, R., Erstad, D. J., Ferriera, D. S., Li, Y., Wang, G., Lanuti, M., Caravan, P., Or, Y. . …
YAP inhibition may be a novel antifibrotic mechanism of FXR agonism, and EDP-305 could be used to treat renal fibrosis.-Li, S., Ghoshal, S., …
Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma.
Jühling F, Hamdane N, Crouchet E, Li S, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, Aikata H, Ono A, Tabrizian P, Schwartz M, Polyak SJ, Davidson I, Schmidl C, Bock C, Schuster C, Chayama K, Pessaux P, Tanabe KK, Hoshida Y, Zeisel MB, Duong FH, Fuchs BC, Baumert TF. Jühling F, et al. Among authors: arora g. Gut. 2021 Jan;70(1):157-169. doi: 10.1136/gutjnl-2019-318918. Epub 2020 Mar 26. Gut. 2021. PMID: 32217639 Free PMC article.
Advanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis.
Zhou IY, Clavijo Jordan V, Rotile NJ, Akam E, Krishnan S, Arora G, Krishnan H, Slattery H, Warner N, Mercaldo N, Farrar CT, Wellen J, Martinez R, Schlerman F, Tanabe KK, Fuchs BC, Caravan P. Zhou IY, et al. Among authors: arora g. Radiology. 2020 Jul;296(1):67-75. doi: 10.1148/radiol.2020192118. Epub 2020 Apr 28. Radiology. 2020. PMID: 32343209 Free PMC article.
Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and Is Measurable with Collagen-Targeted Molecular MRI.
Erstad DJ, Sojoodi M, Taylor MS, Jordan VC, Farrar CT, Axtell AL, Rotile NJ, Jones C, Graham-O'Regan KA, Ferreira DS, Michelakos T, Kontos F, Chawla A, Li S, Ghoshal S, Chen YI, Arora G, Humblet V, Deshpande V, Qadan M, Bardeesy N, Ferrone CR, Lanuti M, Tanabe KK, Caravan P, Fuchs BC. Erstad DJ, et al. Among authors: arora g. Clin Cancer Res. 2020 Sep 15;26(18):5007-5018. doi: 10.1158/1078-0432.CCR-18-1359. Epub 2020 Jul 1. Clin Cancer Res. 2020. PMID: 32611647 Free PMC article.
Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation.
Crouchet E, Li S, Sojoodi M, Bandiera S, Fujiwara N, El Saghire H, Zhu S, Qian T, Rasha FA, Del Zompo F, Barrett SC, Schaeffer E, Oudot MA, Ponsolles C, Durand SC, Ghoshal S, Arora G, Giannone F, Chung RT, Slovic N, Van Renne N, Felli E, Pessaux P, Lupberger J, Pochet N, Schuster C, Tanabe KK, Hoshida Y, Fuchs BC, Baumert TF. Crouchet E, et al. Among authors: arora g. JCI Insight. 2022 Jul 8;7(13):e159254. doi: 10.1172/jci.insight.159254. JCI Insight. 2022. PMID: 35801591 Free PMC article.
Molecular MR Imaging of Renal Fibrogenesis in Mice.
Chen YC, Waghorn PA, Rosales IA, Arora G, Erstad DJ, Rotile NJ, Jones CM, Ferreira DS, Wei L, Martinez RVP, Schlerman FJ, Wellen J, Fuchs BC, Colvin RB, Ay I, Caravan P. Chen YC, et al. Among authors: arora g. J Am Soc Nephrol. 2023 Jul 1;34(7):1159-1165. doi: 10.1681/ASN.0000000000000148. Epub 2023 Apr 24. J Am Soc Nephrol. 2023. PMID: 37094382
Hippo and PI5P4K signaling intersect to control the transcriptional activation of YAP.
Palamiuc L, Johnson JL, Haratipour Z, Loughran RM, Choi WJ, Arora GK, Tieu V, Ly K, Llorente A, Crabtree S, Wong JCY, Ravi A, Wiederhold T, Murad R, Blind RD, Emerling BM. Palamiuc L, et al. Among authors: arora gk. Sci Signal. 2024 May 28;17(838):eado6266. doi: 10.1126/scisignal.ado6266. Epub 2024 May 28. Sci Signal. 2024. PMID: 38805583
543 results