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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Berenjeno IM, Piñeiro R, Castillo SD, Pearce W, McGranahan N, Dewhurst SM, Meniel V, Birkbak NJ, Lau E, Sansregret L, Morelli D, Kanu N, Srinivas S, Graupera M, Parker VER, Montgomery KG, Moniz LS, Scudamore CL, Phillips WA, Semple RK, Clarke A, Swanton C, Vanhaesebroeck B. Berenjeno IM, et al. Among authors: clarke a. Nat Commun. 2017 Nov 24;8(1):1773. doi: 10.1038/s41467-017-02002-4. Nat Commun. 2017. PMID: 29170395 Free PMC article.
Myc deletion rescues Apc deficiency in the small intestine.
Sansom OJ, Meniel VS, Muncan V, Phesse TJ, Wilkins JA, Reed KR, Vass JK, Athineos D, Clevers H, Clarke AR. Sansom OJ, et al. Among authors: clarke ar. Nature. 2007 Apr 5;446(7136):676-9. doi: 10.1038/nature05674. Epub 2007 Mar 21. Nature. 2007. PMID: 17377531
Cited1 deficiency suppresses intestinal tumorigenesis.
Méniel V, Song F, Phesse T, Young M, Poetz O, Parry L, Jenkins JR, Williams GT, Dunwoodie SL, Watson A, Clarke AR. Méniel V, et al. Among authors: clarke ar. PLoS Genet. 2013;9(8):e1003638. doi: 10.1371/journal.pgen.1003638. Epub 2013 Aug 1. PLoS Genet. 2013. PMID: 23935526 Free PMC article.
3,824 results