Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

15 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Berenjeno IM, Piñeiro R, Castillo SD, Pearce W, McGranahan N, Dewhurst SM, Meniel V, Birkbak NJ, Lau E, Sansregret L, Morelli D, Kanu N, Srinivas S, Graupera M, Parker VER, Montgomery KG, Moniz LS, Scudamore CL, Phillips WA, Semple RK, Clarke A, Swanton C, Vanhaesebroeck B. Berenjeno IM, et al. Among authors: dewhurst sm. Nat Commun. 2017 Nov 24;8(1):1773. doi: 10.1038/s41467-017-02002-4. Nat Commun. 2017. PMID: 29170395 Free PMC article.
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
López S, Lim EL, Horswell S, Haase K, Huebner A, Dietzen M, Mourikis TP, Watkins TBK, Rowan A, Dewhurst SM, Birkbak NJ, Wilson GA, Van Loo P, Jamal-Hanjani M; TRACERx Consortium; Swanton C, McGranahan N. López S, et al. Among authors: dewhurst sm. Nat Genet. 2020 Mar;52(3):283-293. doi: 10.1038/s41588-020-0584-7. Epub 2020 Mar 5. Nat Genet. 2020. PMID: 32139907 Free PMC article.
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53.
Crockford A, Zalmas LP, Grönroos E, Dewhurst SM, McGranahan N, Cuomo ME, Encheva V, Snijders AP, Begum J, Purewal S, Cerveira J, Patel H, Renshaw MJ, Swanton C. Crockford A, et al. Among authors: dewhurst sm. Ann Oncol. 2017 Jan 1;28(1):149-156. doi: 10.1093/annonc/mdw612. Ann Oncol. 2017. PMID: 28177473 Free PMC article.
Tetraploidy and CIN: a dangerous combination.
Dewhurst S, Swanton C. Dewhurst S, et al. Cell Cycle. 2015;14(20):3217. doi: 10.1080/15384101.2015.1084208. Cell Cycle. 2015. PMID: 26517196 Free PMC article. No abstract available.
Cancer: evolution within a lifetime.
Gerlinger M, McGranahan N, Dewhurst SM, Burrell RA, Tomlinson I, Swanton C. Gerlinger M, et al. Among authors: dewhurst sm. Annu Rev Genet. 2014;48:215-36. doi: 10.1146/annurev-genet-120213-092314. Epub 2014 Oct 1. Annu Rev Genet. 2014. PMID: 25292359 Review.
Replication stress links structural and numerical cancer chromosomal instability.
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C. Burrell RA, et al. Among authors: dewhurst sm. Nature. 2013 Feb 28;494(7438):492-496. doi: 10.1038/nature11935. Nature. 2013. PMID: 23446422 Free PMC article.
Pervasive chromosomal instability and karyotype order in tumour evolution.
Watkins TBK, Lim EL, Petkovic M, Elizalde S, Birkbak NJ, Wilson GA, Moore DA, Grönroos E, Rowan A, Dewhurst SM, Demeulemeester J, Dentro SC, Horswell S, Au L, Haase K, Escudero M, Rosenthal R, Bakir MA, Xu H, Litchfield K, Lu WT, Mourikis TP, Dietzen M, Spain L, Cresswell GD, Biswas D, Lamy P, Nordentoft I, Harbst K, Castro-Giner F, Yates LR, Caramia F, Jaulin F, Vicier C, Tomlinson IPM, Brastianos PK, Cho RJ, Bastian BC, Dyrskjøt L, Jönsson GB, Savas P, Loi S, Campbell PJ, Andre F, Luscombe NM, Steeghs N, Tjan-Heijnen VCG, Szallasi Z, Turajlic S, Jamal-Hanjani M, Van Loo P, Bakhoum SF, Schwarz RF, McGranahan N, Swanton C. Watkins TBK, et al. Among authors: dewhurst sm. Nature. 2020 Nov;587(7832):126-132. doi: 10.1038/s41586-020-2698-6. Epub 2020 Sep 2. Nature. 2020. PMID: 32879494 Free PMC article.
APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.
Sansregret L, Patterson JO, Dewhurst S, López-García C, Koch A, McGranahan N, Chao WCH, Barry DJ, Rowan A, Instrell R, Horswell S, Way M, Howell M, Singleton MR, Medema RH, Nurse P, Petronczki M, Swanton C. Sansregret L, et al. Cancer Discov. 2017 Feb;7(2):218-233. doi: 10.1158/2159-8290.CD-16-0645. Epub 2017 Jan 9. Cancer Discov. 2017. PMID: 28069571 Free PMC article.
Structural variant evolution after telomere crisis.
Dewhurst SM, Yao X, Rosiene J, Tian H, Behr J, Bosco N, Takai KK, de Lange T, Imieliński M. Dewhurst SM, et al. Nat Commun. 2021 Apr 7;12(1):2093. doi: 10.1038/s41467-021-21933-7. Nat Commun. 2021. PMID: 33828097 Free PMC article.
15 results