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Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons.
Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, Fuertes FD, Scheuermann RH, Lee J, Lein ES, Schork N, McConnell MJ, Gage FH, Lasken RS. Krishnaswami SR, et al. Nat Protoc. 2016 Mar;11(3):499-524. doi: 10.1038/nprot.2016.015. Epub 2016 Feb 18. Nat Protoc. 2016. PMID: 26890679 Free PMC article.
Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation.
Close JL, Yao Z, Levi BP, Miller JA, Bakken TE, Menon V, Ting JT, Wall A, Krostag AR, Thomsen ER, Nelson AM, Mich JK, Hodge RD, Shehata SI, Glass IA, Bort S, Shapovalova NV, Ngo NK, Grimley JS, Phillips JW, Thompson CL, Ramanathan S, Lein E. Close JL, et al. Among authors: lein e. Neuron. 2017 Mar 8;93(5):1035-1048.e5. doi: 10.1016/j.neuron.2017.02.014. Neuron. 2017. PMID: 28279351 Free PMC article.
Genetic identification of brain cell types underlying schizophrenia.
Skene NG, Bryois J, Bakken TE, Breen G, Crowley JJ, Gaspar HA, Giusti-Rodriguez P, Hodge RD, Miller JA, Muñoz-Manchado AB, O'Donovan MC, Owen MJ, Pardiñas AF, Ryge J, Walters JTR, Linnarsson S, Lein ES; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Sullivan PF, Hjerling-Leffler J. Skene NG, et al. Among authors: lein es. Nat Genet. 2018 Jun;50(6):825-833. doi: 10.1038/s41588-018-0129-5. Epub 2018 May 21. Nat Genet. 2018. PMID: 29785013 Free PMC article.
Single-nucleus and single-cell transcriptomes compared in matched cortical cell types.
Bakken TE, Hodge RD, Miller JA, Yao Z, Nguyen TN, Aevermann B, Barkan E, Bertagnolli D, Casper T, Dee N, Garren E, Goldy J, Graybuck LT, Kroll M, Lasken RS, Lathia K, Parry S, Rimorin C, Scheuermann RH, Schork NJ, Shehata SI, Tieu M, Phillips JW, Bernard A, Smith KA, Zeng H, Lein ES, Tasic B. Bakken TE, et al. Among authors: lein es. PLoS One. 2018 Dec 26;13(12):e0209648. doi: 10.1371/journal.pone.0209648. eCollection 2018. PLoS One. 2018. PMID: 30586455 Free PMC article.
Conserved cell types with divergent features in human versus mouse cortex.
Hodge RD, Bakken TE, Miller JA, Smith KA, Barkan ER, Graybuck LT, Close JL, Long B, Johansen N, Penn O, Yao Z, Eggermont J, Höllt T, Levi BP, Shehata SI, Aevermann B, Beller A, Bertagnolli D, Brouner K, Casper T, Cobbs C, Dalley R, Dee N, Ding SL, Ellenbogen RG, Fong O, Garren E, Goldy J, Gwinn RP, Hirschstein D, Keene CD, Keshk M, Ko AL, Lathia K, Mahfouz A, Maltzer Z, McGraw M, Nguyen TN, Nyhus J, Ojemann JG, Oldre A, Parry S, Reynolds S, Rimorin C, Shapovalova NV, Somasundaram S, Szafer A, Thomsen ER, Tieu M, Quon G, Scheuermann RH, Yuste R, Sunkin SM, Lelieveldt B, Feng D, Ng L, Bernard A, Hawrylycz M, Phillips JW, Tasic B, Zeng H, Jones AR, Koch C, Lein ES. Hodge RD, et al. Among authors: lein es. Nature. 2019 Sep;573(7772):61-68. doi: 10.1038/s41586-019-1506-7. Epub 2019 Aug 21. Nature. 2019. PMID: 31435019 Free PMC article.
Parallel RNA and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain.
Huang AY, Li P, Rodin RE, Kim SN, Dou Y, Kenny CJ, Akula SK, Hodge RD, Bakken TE, Miller JA, Lein ES, Park PJ, Lee EA, Walsh CA. Huang AY, et al. Among authors: lein es. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):13886-13895. doi: 10.1073/pnas.2006163117. Epub 2020 Jun 10. Proc Natl Acad Sci U S A. 2020. PMID: 32522880 Free PMC article.
164 results