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Page 1
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.
Solimena M, Schulte AM, Marselli L, Ehehalt F, Richter D, Kleeberg M, Mziaut H, Knoch KP, Parnis J, Bugliani M, Siddiq A, Jörns A, Burdet F, Liechti R, Suleiman M, Margerie D, Syed F, Distler M, Grützmann R, Petretto E, Moreno-Moral A, Wegbrod C, Sönmez A, Pfriem K, Friedrich A, Meinel J, Wollheim CB, Baretton GB, Scharfmann R, Nogoceke E, Bonifacio E, Sturm D, Meyer-Puttlitz B, Boggi U, Saeger HD, Filipponi F, Lesche M, Meda P, Dahl A, Wigger L, Xenarios I, Falchi M, Thorens B, Weitz J, Bokvist K, Lenzen S, Rutter GA, Froguel P, von Bülow M, Ibberson M, Marchetti P. Solimena M, et al. Among authors: syed f. Diabetologia. 2018 Mar;61(3):641-657. doi: 10.1007/s00125-017-4500-3. Epub 2017 Nov 28. Diabetologia. 2018. PMID: 29185012 Free PMC article.
From genotype to human β cell phenotype and beyond.
Marchetti P, Syed F, Suleiman M, Bugliani M, Marselli L. Marchetti P, et al. Among authors: syed f. Islets. 2012 Sep-Oct;4(5):323-32. doi: 10.4161/isl.22282. Epub 2012 Sep 1. Islets. 2012. PMID: 23073174 Free PMC article. Review.
Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.
Bugliani M, Liechti R, Cheon H, Suleiman M, Marselli L, Kirkpatrick C, Filipponi F, Boggi U, Xenarios I, Syed F, Ladriere L, Wollheim C, Lee MS, Marchetti P. Bugliani M, et al. Among authors: syed f. Mol Cell Endocrinol. 2013 Mar 10;367(1-2):1-10. doi: 10.1016/j.mce.2012.12.001. Epub 2012 Dec 12. Mol Cell Endocrinol. 2013. PMID: 23246353
Direct effects of rosuvastatin on pancreatic human beta cells.
Bugliani M, Syed F, Masini M, Marselli L, Suleiman M, Novelli M, Filipponi F, Boggi U, Masiello P, De Tata V, Marchetti P. Bugliani M, et al. Among authors: syed f. Acta Diabetol. 2013 Dec;50(6):983-5. doi: 10.1007/s00592-013-0465-y. Epub 2013 Mar 17. Acta Diabetol. 2013. PMID: 23503985 No abstract available.
β-Cell inflammation in human type 2 diabetes and the role of autophagy.
Marselli L, Bugliani M, Suleiman M, Olimpico F, Masini M, Petrini M, Boggi U, Filipponi F, Syed F, Marchetti P. Marselli L, et al. Among authors: syed f. Diabetes Obes Metab. 2013 Sep;15 Suppl 3:130-6. doi: 10.1111/dom.12152. Diabetes Obes Metab. 2013. PMID: 24003929 Review.
Are we overestimating the loss of beta cells in type 2 diabetes?
Marselli L, Suleiman M, Masini M, Campani D, Bugliani M, Syed F, Martino L, Focosi D, Scatena F, Olimpico F, Filipponi F, Masiello P, Boggi U, Marchetti P. Marselli L, et al. Among authors: syed f. Diabetologia. 2014 Feb;57(2):362-5. doi: 10.1007/s00125-013-3098-3. Diabetologia. 2014. PMID: 24233056
Mast cells infiltrate pancreatic islets in human type 1 diabetes.
Martino L, Masini M, Bugliani M, Marselli L, Suleiman M, Boggi U, Nogueira TC, Filipponi F, Occhipinti M, Campani D, Dotta F, Syed F, Eizirik DL, Marchetti P, De Tata V. Martino L, et al. Among authors: syed f. Diabetologia. 2015 Nov;58(11):2554-62. doi: 10.1007/s00125-015-3734-1. Epub 2015 Aug 15. Diabetologia. 2015. PMID: 26276263
Labeling and Tracking of Human Pancreatic Islets Using Carbon Nanotubes.
Syed F, Riggio C, Masini M, Bugliani M, Battaglia V, Novelli M, Suleiman M, Vittorio O, Boggi U, Filipponi F, Marselli L, Bartolozzi C, Masiello P, Raffa V, Marchetti P. Syed F, et al. J Biomed Nanotechnol. 2015 Apr;11(4):730-8. doi: 10.1166/jbn.2015.1952. J Biomed Nanotechnol. 2015. PMID: 26310079
DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes.
Bugliani M, Syed F, Paula FMM, Omar BA, Suleiman M, Mossuto S, Grano F, Cardarelli F, Boggi U, Vistoli F, Filipponi F, De Simone P, Marselli L, De Tata V, Ahren B, Eizirik DL, Marchetti P. Bugliani M, et al. Among authors: syed f. Mol Cell Endocrinol. 2018 Sep 15;473:186-193. doi: 10.1016/j.mce.2018.01.019. Epub 2018 Feb 1. Mol Cell Endocrinol. 2018. PMID: 29409957
Episodic β-cell death and dedifferentiation during diet-induced obesity and dysglycemia in male mice.
Tersey SA, Levasseur EM, Syed F, Farb TB, Orr KS, Nelson JB, Shaw JL, Bokvist K, Mather KJ, Mirmira RG. Tersey SA, et al. Among authors: syed f. FASEB J. 2018 May 29;32(11):fj201800150RR. doi: 10.1096/fj.201800150RR. Online ahead of print. FASEB J. 2018. PMID: 29812970 Free PMC article.
In conclusion, early episodic beta-cell death may be a feature of cellular turnover correlated with changes in glycemia during beta-cell mass accrual in obesity, whereas beta-cell dedifferentiation may be a feature seen later in established disease.-Tersey, S. A., Levasseur, E. M …
In conclusion, early episodic beta-cell death may be a feature of cellular turnover correlated with changes in glycemia during beta-cell mas …
452 results