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Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
Costa Franco MM, Marim F, Guimarães ES, Assis NRG, Cerqueira DM, Alves-Silva J, Harms J, Splitter G, Smith J, Kanneganti TD, de Queiroz NMGP, Gutman D, Barber GN, Oliveira SC. Costa Franco MM, et al. Among authors: barber gn. J Immunol. 2018 Jan 15;200(2):607-622. doi: 10.4049/jimmunol.1700725. Epub 2017 Dec 4. J Immunol. 2018. PMID: 29203515 Free PMC article.
Brucella suppress STING expression via miR-24 to enhance infection.
Khan M, Harms JS, Liu Y, Eickhoff J, Tan JW, Hu T, Cai F, Guimaraes E, Oliveira SC, Dahl R, Cheng Y, Gutman D, Barber GN, Splitter GA, Smith JA. Khan M, et al. Among authors: barber gn. PLoS Pathog. 2020 Oct 27;16(10):e1009020. doi: 10.1371/journal.ppat.1009020. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33108406 Free PMC article.
The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation.
Canesso MCC, Lemos L, Neves TC, Marim FM, Castro TBR, Veloso ÉS, Queiroz CP, Ahn J, Santiago HC, Martins FS, Alves-Silva J, Ferreira E, Cara DC, Vieira AT, Barber GN, Oliveira SC, Faria AMC. Canesso MCC, et al. Among authors: barber gn. Mucosal Immunol. 2018 May;11(3):820-834. doi: 10.1038/mi.2017.88. Epub 2017 Dec 20. Mucosal Immunol. 2018. PMID: 29346345 Free article.
STING manifests self DNA-dependent inflammatory disease.
Ahn J, Gutman D, Saijo S, Barber GN. Ahn J, et al. Among authors: barber gn. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19386-91. doi: 10.1073/pnas.1215006109. Epub 2012 Nov 6. Proc Natl Acad Sci U S A. 2012. PMID: 23132945 Free PMC article.
191 results