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Adipose tissue mitochondrial capacity associates with long-term weight loss success.
Jokinen R, Rinnankoski-Tuikka R, Kaye S, Saarinen L, Heinonen S, Myöhänen M, Rappou E, Jukarainen S, Rissanen A, Pessia A, Velagapudi V, Virtanen KA, Pirinen E, Pietiläinen KH. Jokinen R, et al. Among authors: rappou e. Int J Obes (Lond). 2018 Apr;42(4):817-825. doi: 10.1038/ijo.2017.299. Epub 2017 Dec 5. Int J Obes (Lond). 2018. PMID: 29203860 Clinical Trial.
Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.
Rappou E, Jukarainen S, Rinnankoski-Tuikka R, Kaye S, Heinonen S, Hakkarainen A, Lundbom J, Lundbom N, Saunavaara V, Rissanen A, Virtanen KA, Pirinen E, Pietiläinen KH. Rappou E, et al. J Clin Endocrinol Metab. 2016 Mar;101(3):1263-73. doi: 10.1210/jc.2015-3054. Epub 2016 Jan 13. J Clin Endocrinol Metab. 2016. PMID: 26760174 Clinical Trial.
Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.
Jukarainen S, Heinonen S, Rämö JT, Rinnankoski-Tuikka R, Rappou E, Tummers M, Muniandy M, Hakkarainen A, Lundbom J, Lundbom N, Kaprio J, Rissanen A, Pirinen E, Pietiläinen KH. Jukarainen S, et al. Among authors: rappou e. J Clin Endocrinol Metab. 2016 Jan;101(1):275-83. doi: 10.1210/jc.2015-3095. Epub 2015 Nov 17. J Clin Endocrinol Metab. 2016. PMID: 26574954
Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1α.
Hyrskyluoto A, Bruelle C, Lundh SH, Do HT, Kivinen J, Rappou E, Reijonen S, Waltimo T, Petersén Å, Lindholm D, Korhonen L. Hyrskyluoto A, et al. Among authors: rappou e. Hum Mol Genet. 2014 Nov 15;23(22):5928-39. doi: 10.1093/hmg/ddu317. Epub 2014 Jun 20. Hum Mol Genet. 2014. PMID: 24951540
Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in Parkinson's disease.
Virachit S, Mathews KJ, Cottam V, Werry E, Galli E, Rappou E, Lindholm P, Saarma M, Halliday GM, Shannon Weickert C, Double KL. Virachit S, et al. Among authors: rappou e. Brain Pathol. 2019 Nov;29(6):813-825. doi: 10.1111/bpa.12730. Epub 2019 Jun 14. Brain Pathol. 2019. PMID: 31033033 Free PMC article.