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Short Aβ peptides attenuate Aβ42 toxicity in vivo.
Moore BD, Martin J, de Mena L, Sanchez J, Cruz PE, Ceballos-Diaz C, Ladd TB, Ran Y, Levites Y, Kukar TL, Kurian JJ, McKenna R, Koo EH, Borchelt DR, Janus C, Rincon-Limas D, Fernandez-Funez P, Golde TE. Moore BD, et al. Among authors: kukar tl. J Exp Med. 2018 Jan 2;215(1):283-301. doi: 10.1084/jem.20170600. Epub 2017 Dec 5. J Exp Med. 2018. PMID: 29208777 Free PMC article.
Steroids as γ-secretase modulators.
Jung JI, Ladd TB, Kukar T, Price AR, Moore BD, Koo EH, Golde TE, Felsenstein KM. Jung JI, et al. FASEB J. 2013 Sep;27(9):3775-85. doi: 10.1096/fj.12-225649. Epub 2013 May 28. FASEB J. 2013. PMID: 23716494 Free PMC article.
Medicine. Avoiding unintended toxicity.
Golde TE, Kukar TL. Golde TE, et al. Among authors: kukar tl. Science. 2009 May 1;324(5927):603-4. doi: 10.1126/science.1174267. Science. 2009. PMID: 19407192 No abstract available.
Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region.
Kukar TL, Ladd TB, Robertson P, Pintchovski SA, Moore B, Bann MA, Ren Z, Jansen-West K, Malphrus K, Eggert S, Maruyama H, Cottrell BA, Das P, Basi GS, Koo EH, Golde TE. Kukar TL, et al. J Biol Chem. 2011 Nov 18;286(46):39804-12. doi: 10.1074/jbc.M111.274696. Epub 2011 Aug 25. J Biol Chem. 2011. PMID: 21868378 Free PMC article.
40 results