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Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide.
Sci Rep. 2017 Dec 6;7(1):17056. doi: 10.1038/s41598-017-17316-y.
Sci Rep. 2017.
PMID: 29213085
Free PMC article.
New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids.
Arukuusk P, Pärnaste L, Oskolkov N, Copolovici DM, Margus H, Padari K, Möll K, Maslovskaja J, Tegova R, Kivi G, Tover A, Pooga M, Ustav M, Langel U.
Arukuusk P, et al. Among authors: parnaste l.
Biochim Biophys Acta. 2013 May;1828(5):1365-73. doi: 10.1016/j.bbamem.2013.01.011. Epub 2013 Jan 26.
Biochim Biophys Acta. 2013.
PMID: 23357356
Free article.
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Differential endosomal pathways for radically modified peptide vectors.
Arukuusk P, Pärnaste L, Margus H, Eriksson NK, Vasconcelos L, Padari K, Pooga M, Langel U.
Arukuusk P, et al. Among authors: parnaste l.
Bioconjug Chem. 2013 Oct 16;24(10):1721-32. doi: 10.1021/bc4002757. Epub 2013 Sep 16.
Bioconjug Chem. 2013.
PMID: 23981119
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Effects of cargo molecules on membrane perturbation caused by transportan10 based cell-penetrating peptides.
Vasconcelos L, Madani F, Arukuusk P, Pärnaste L, Gräslund A, Langel U.
Vasconcelos L, et al. Among authors: parnaste l.
Biochim Biophys Acta. 2014 Dec;1838(12):3118-29. doi: 10.1016/j.bbamem.2014.08.011. Epub 2014 Aug 15.
Biochim Biophys Acta. 2014.
PMID: 25135660
Free article.
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PepFects and NickFects for the Intracellular Delivery of Nucleic Acids.
Arukuusk P, Pärnaste L, Hällbrink M, Langel Ü.
Arukuusk P, et al. Among authors: parnaste l.
Methods Mol Biol. 2015;1324:303-15. doi: 10.1007/978-1-4939-2806-4_19.
Methods Mol Biol. 2015.
PMID: 26202277
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Methods to follow intracellular trafficking of cell-penetrating peptides.
Pärnaste L, Arukuusk P, Zagato E, Braeckmans K, Langel Ü.
Pärnaste L, et al.
J Drug Target. 2016;24(6):508-19. doi: 10.3109/1061186X.2015.1095194. Epub 2015 Oct 12.
J Drug Target. 2016.
PMID: 26460120
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The Formation of Nanoparticles between Small Interfering RNA and Amphipathic Cell-Penetrating Peptides.
Pärnaste L, Arukuusk P, Langel K, Tenson T, Langel Ü.
Pärnaste L, et al.
Mol Ther Nucleic Acids. 2017 Jun 16;7:1-10. doi: 10.1016/j.omtn.2017.02.003. Epub 2017 Feb 10.
Mol Ther Nucleic Acids. 2017.
PMID: 28624185
Free PMC article.
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Formulation of Stable and Homogeneous Cell-Penetrating Peptide NF55 Nanoparticles for Efficient Gene Delivery In Vivo.
Freimann K, Arukuusk P, Kurrikoff K, Pärnaste L, Raid R, Piirsoo A, Pooga M, Langel Ü.
Freimann K, et al. Among authors: parnaste l.
Mol Ther Nucleic Acids. 2018 Mar 2;10:28-35. doi: 10.1016/j.omtn.2017.10.011. Epub 2017 Oct 20.
Mol Ther Nucleic Acids. 2018.
PMID: 29499941
Free PMC article.
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