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The use of genetically engineered model systems for research on human aging.
Lepperdinger G, Berger P, Breitenbach M, Frohlich KU, Grillari J, Grubeck-Loebenstein B, Madeo F, Minois N, Zwerschke W, Jansen-Durr P. Lepperdinger G, et al. Among authors: breitenbach m. Front Biosci. 2008 May 1;13:7022-31. doi: 10.2741/3207. Front Biosci. 2008. PMID: 18508713
Identification of evolutionarily conserved genetic regulators of cellular aging.
Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P. Laschober GT, et al. Among authors: breitenbach m. Aging Cell. 2010 Dec;9(6):1084-97. doi: 10.1111/j.1474-9726.2010.00637.x. Epub 2010 Oct 28. Aging Cell. 2010. PMID: 20883526 Free PMC article.
Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.
Schosserer M, Minois N, Angerer TB, Amring M, Dellago H, Harreither E, Calle-Perez A, Pircher A, Gerstl MP, Pfeifenberger S, Brandl C, Sonntagbauer M, Kriegner A, Linder A, Weinhäusel A, Mohr T, Steiger M, Mattanovich D, Rinnerthaler M, Karl T, Sharma S, Entian KD, Kos M, Breitenbach M, Wilson IB, Polacek N, Grillari-Voglauer R, Breitenbach-Koller L, Grillari J. Schosserer M, et al. Among authors: breitenbach m, breitenbach koller l. Nat Commun. 2015 Jan 30;6:6158. doi: 10.1038/ncomms7158. Nat Commun. 2015. PMID: 25635753 Free PMC article.
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging.
Hackl M, Brunner S, Fortschegger K, Schreiner C, Micutkova L, Mück C, Laschober GT, Lepperdinger G, Sampson N, Berger P, Herndler-Brandstetter D, Wieser M, Kühnel H, Strasser A, Rinnerthaler M, Breitenbach M, Mildner M, Eckhart L, Tschachler E, Trost A, Bauer JW, Papak C, Trajanoski Z, Scheideler M, Grillari-Voglauer R, Grubeck-Loebenstein B, Jansen-Dürr P, Grillari J. Hackl M, et al. Among authors: breitenbach m. Aging Cell. 2010 Apr;9(2):291-6. doi: 10.1111/j.1474-9726.2010.00549.x. Epub 2010 Jan 18. Aging Cell. 2010. PMID: 20089119 Free PMC article.
Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.
Schosserer M, Minois N, Angerer TB, Amring M, Dellago H, Harreither E, Calle-Perez A, Pircher A, Peter Gerstl M, Pfeifenberger S, Brandl C, Sonntagbauer M, Kriegner A, Linder A, Weinhäusel A, Mohr T, Steiger M, Mattanovich D, Rinnerthaler M, Karl T, Sharma S, Entian KD, Kos M, Breitenbach M, Wilson IB, Polacek N, Grillari-Voglauer R, Breitenbach-Koller L, Grillari J. Schosserer M, et al. Among authors: breitenbach m, breitenbach koller l. Nat Commun. 2016 May 11;7:11530. doi: 10.1038/ncomms11530. Nat Commun. 2016. PMID: 27167997 Free PMC article. No abstract available.
A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.
Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M. Timmermann B, et al. Among authors: breitenbach m. Aging (Albany NY). 2010 Aug;2(8):475-86. doi: 10.18632/aging.100187. Aging (Albany NY). 2010. PMID: 20729566 Free PMC article.
Editorial: Cancer Models.
Breitenbach M, Hoffmann J. Breitenbach M, et al. Front Oncol. 2018 Oct 3;8:401. doi: 10.3389/fonc.2018.00401. eCollection 2018. Front Oncol. 2018. PMID: 30338241 Free PMC article. No abstract available.
The Human NADPH Oxidase, Nox4, Regulates Cytoskeletal Organization in Two Cancer Cell Lines, HepG2 and SH-SY5Y.
Auer S, Rinnerthaler M, Bischof J, Streubel MK, Breitenbach-Koller H, Geisberger R, Aigner E, Cadamuro J, Richter K, Sopjani M, Haschke-Becher E, Felder TK, Breitenbach M. Auer S, et al. Among authors: breitenbach koller h, breitenbach m. Front Oncol. 2017 May 31;7:111. doi: 10.3389/fonc.2017.00111. eCollection 2017. Front Oncol. 2017. PMID: 28620580 Free PMC article.
210 results