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Inhibiting the Ca2+ Influx Induced by Human CSF.
Drews A, De S, Flagmeier P, Wirthensohn DC, Chen WH, Whiten DR, Rodrigues M, Vincke C, Muyldermans S, Paterson RW, Slattery CF, Fox NC, Schott JM, Zetterberg H, Dobson CM, Gandhi S, Klenerman D. Drews A, et al. Among authors: gandhi s. Cell Rep. 2017 Dec 12;21(11):3310-3316. doi: 10.1016/j.celrep.2017.11.057. Cell Rep. 2017. PMID: 29241555 Free PMC article.
Oculoleptomeningeal Amyloidosis associated with transthyretin Leu12Pro in an African patient.
McColgan P, Viegas S, Gandhi S, Bull K, Tudor R, Sheikh F, Pinney J, Fontana M, Rowczenio D, Gillmore JD, Gilbertson JA, Whelan CJ, Shah S, Jaunmuktane Z, Holton JL, Schott JM, Werring DJ, Hawkins PN, Reilly MM. McColgan P, et al. Among authors: gandhi s. J Neurol. 2015 Jan;262(1):228-34. doi: 10.1007/s00415-014-7594-2. Epub 2014 Dec 9. J Neurol. 2015. PMID: 25488473 Free PMC article.
Lipid peroxidation is essential for α-synuclein-induced cell death.
Angelova PR, Horrocks MH, Klenerman D, Gandhi S, Abramov AY, Shchepinov MS. Angelova PR, et al. Among authors: gandhi s. J Neurochem. 2015 May;133(4):582-9. doi: 10.1111/jnc.13024. Epub 2015 Mar 1. J Neurochem. 2015. PMID: 25580849 Free PMC article.
Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease.
Deas E, Cremades N, Angelova PR, Ludtmann MH, Yao Z, Chen S, Horrocks MH, Banushi B, Little D, Devine MJ, Gissen P, Klenerman D, Dobson CM, Wood NW, Gandhi S, Abramov AY. Deas E, et al. Among authors: gandhi s. Antioxid Redox Signal. 2016 Mar 1;24(7):376-91. doi: 10.1089/ars.2015.6343. Epub 2016 Feb 1. Antioxid Redox Signal. 2016. PMID: 26564470 Free PMC article.
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids.
Horrocks MH, Lee SF, Gandhi S, Magdalinou NK, Chen SW, Devine MJ, Tosatto L, Kjaergaard M, Beckwith JS, Zetterberg H, Iljina M, Cremades N, Dobson CM, Wood NW, Klenerman D. Horrocks MH, et al. Among authors: gandhi s. ACS Chem Neurosci. 2016 Mar 16;7(3):399-406. doi: 10.1021/acschemneuro.5b00324. Epub 2016 Feb 4. ACS Chem Neurosci. 2016. PMID: 26800462 Free PMC article.
Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading.
Iljina M, Garcia GA, Horrocks MH, Tosatto L, Choi ML, Ganzinger KA, Abramov AY, Gandhi S, Wood NW, Cremades N, Dobson CM, Knowles TP, Klenerman D. Iljina M, et al. Among authors: gandhi s. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1206-15. doi: 10.1073/pnas.1524128113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884195 Free PMC article.
Ca2+ is a key factor in α-synuclein-induced neurotoxicity.
Angelova PR, Ludtmann MH, Horrocks MH, Negoda A, Cremades N, Klenerman D, Dobson CM, Wood NW, Pavlov EV, Gandhi S, Abramov AY. Angelova PR, et al. Among authors: gandhi s. J Cell Sci. 2016 May 1;129(9):1792-801. doi: 10.1242/jcs.180737. Epub 2016 Mar 17. J Cell Sci. 2016. PMID: 26989132 Free PMC article.
2,064 results