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Inhibiting the Ca2+ Influx Induced by Human CSF.
Drews A, De S, Flagmeier P, Wirthensohn DC, Chen WH, Whiten DR, Rodrigues M, Vincke C, Muyldermans S, Paterson RW, Slattery CF, Fox NC, Schott JM, Zetterberg H, Dobson CM, Gandhi S, Klenerman D. Drews A, et al. Among authors: klenerman d. Cell Rep. 2017 Dec 12;21(11):3310-3316. doi: 10.1016/j.celrep.2017.11.057. Cell Rep. 2017. PMID: 29241555 Free PMC article.
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D. Cremades N, et al. Among authors: klenerman d. Cell. 2012 May 25;149(5):1048-59. doi: 10.1016/j.cell.2012.03.037. Cell. 2012. PMID: 22632969 Free PMC article.
Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage.
Narayan P, Holmström KM, Kim DH, Whitcomb DJ, Wilson MR, St George-Hyslop P, Wood NW, Dobson CM, Cho K, Abramov AY, Klenerman D. Narayan P, et al. Among authors: klenerman d. Biochemistry. 2014 Apr 22;53(15):2442-53. doi: 10.1021/bi401606f. Epub 2014 Apr 9. Biochemistry. 2014. PMID: 24717093 Free PMC article.
Lipid peroxidation is essential for α-synuclein-induced cell death.
Angelova PR, Horrocks MH, Klenerman D, Gandhi S, Abramov AY, Shchepinov MS. Angelova PR, et al. Among authors: klenerman d. J Neurochem. 2015 May;133(4):582-9. doi: 10.1111/jnc.13024. Epub 2015 Mar 1. J Neurochem. 2015. PMID: 25580849 Free PMC article.
261 results