Muyldermans S - Search Results

1

Inhibiting the Ca²⁺ Influx Induced by Human CSF.

Drews A, De S, Flagmeier P, Wirthensohn DC, Chen WH, Whiten DR, Rodrigues M, Vincke C, Muyldermans S, Paterson RW, Slattery CF, Fox NC, Schott JM, Zetterberg H, Dobson CM, Gandhi S, Klenerman D. Drews A, et al. Among authors: muyldermans s. Cell Rep. 2017 Dec 12;21(11):3310-3316. doi: 10.1016/j.celrep.2017.11.057. Cell Rep. 2017. PMID: 29241555 Free PMC article.

2

A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.

Dumoulin M, Last AM, Desmyter A, Decanniere K, Canet D, Larsson G, Spencer A, Archer DB, Sasse J, Muyldermans S, Wyns L, Redfield C, Matagne A, Robinson CV, Dobson CM. Dumoulin M, et al. Among authors: muyldermans s. Nature. 2003 Aug 14;424(6950):783-8. doi: 10.1038/nature01870. Nature. 2003. PMID: 12917687 Free article.

3

Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.

Dumoulin M, Canet D, Last AM, Pardon E, Archer DB, Muyldermans S, Wyns L, Matagne A, Robinson CV, Redfield C, Dobson CM. Dumoulin M, et al. Among authors: muyldermans s. J Mol Biol. 2005 Feb 25;346(3):773-88. doi: 10.1016/j.jmb.2004.11.020. Epub 2004 Nov 24. J Mol Biol. 2005. PMID: 15713462 Free article.

4

Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.

Conrath K, Vincke C, Stijlemans B, Schymkowitz J, Decanniere K, Wyns L, Muyldermans S, Loris R. Conrath K, et al. Among authors: muyldermans s. J Mol Biol. 2005 Jul 1;350(1):112-25. doi: 10.1016/j.jmb.2005.04.050. J Mol Biol. 2005. PMID: 15913651

5

Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.

Chan PH, Pardon E, Menzer L, De Genst E, Kumita JR, Christodoulou J, Saerens D, Brans A, Bouillenne F, Archer DB, Robinson CV, Muyldermans S, Matagne A, Redfield C, Wyns L, Dobson CM, Dumoulin M. Chan PH, et al. Among authors: muyldermans s. Biochemistry. 2008 Oct 21;47(42):11041-54. doi: 10.1021/bi8005797. Epub 2008 Sep 25. Biochemistry. 2008. PMID: 18816062

6

General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.

Vincke C, Loris R, Saerens D, Martinez-Rodriguez S, Muyldermans S, Conrath K. Vincke C, et al. Among authors: muyldermans s. J Biol Chem. 2009 Jan 30;284(5):3273-3284. doi: 10.1074/jbc.M806889200. Epub 2008 Nov 14. J Biol Chem. 2009. PMID: 19010777 Free article.

7

A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire.

Deschacht N, De Groeve K, Vincke C, Raes G, De Baetselier P, Muyldermans S. Deschacht N, et al. Among authors: muyldermans s. J Immunol. 2010 May 15;184(10):5696-704. doi: 10.4049/jimmunol.0903722. Epub 2010 Apr 19. J Immunol. 2010. PMID: 20404276

8

In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT.

Vaneycken I, Govaert J, Vincke C, Caveliers V, Lahoutte T, De Baetselier P, Raes G, Bossuyt A, Muyldermans S, Devoogdt N. Vaneycken I, et al. Among authors: muyldermans s. J Nucl Med. 2010 Jul;51(7):1099-106. doi: 10.2967/jnumed.109.069823. Epub 2010 Jun 16. J Nucl Med. 2010. PMID: 20554727 Free article.

9

Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer.

Vaneycken I, Devoogdt N, Van Gassen N, Vincke C, Xavier C, Wernery U, Muyldermans S, Lahoutte T, Caveliers V. Vaneycken I, et al. Among authors: muyldermans s. FASEB J. 2011 Jul;25(7):2433-46. doi: 10.1096/fj.10-180331. Epub 2011 Apr 8. FASEB J. 2011. PMID: 21478264

10

Dual beneficial effect of interloop disulfide bond for single domain antibody fragments.

Govaert J, Pellis M, Deschacht N, Vincke C, Conrath K, Muyldermans S, Saerens D. Govaert J, et al. Among authors: muyldermans s. J Biol Chem. 2012 Jan 13;287(3):1970-9. doi: 10.1074/jbc.M111.242818. Epub 2011 Nov 29. J Biol Chem. 2012. PMID: 22128183 Free PMC article.

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