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Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B.
Miesbach W, Meijer K, Coppens M, Kampmann P, Klamroth R, Schutgens R, Tangelder M, Castaman G, Schwäble J, Bonig H, Seifried E, Cattaneo F, Meyer C, Leebeek FWG. Miesbach W, et al. Among authors: schutgens r. Blood. 2018 Mar 1;131(9):1022-1031. doi: 10.1182/blood-2017-09-804419. Epub 2017 Dec 15. Blood. 2018. PMID: 29246900 Free PMC article. Clinical Trial.
Coronary artery calcification in hemophilia A: no evidence for a protective effect of factor VIII deficiency on atherosclerosis.
Tuinenburg A, Rutten A, Kavousi M, Leebeek FW, Ypma PF, Laros-van Gorkom BA, Nijziel MR, Kamphuisen PW, Mauser-Bunschoten EP, Roosendaal G, Biesma DH, van der Lugt A, Hofman A, Witteman JC, Bots ML, Schutgens RE. Tuinenburg A, et al. Among authors: schutgens re. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):799-804. doi: 10.1161/ATVBAHA.111.238162. Epub 2011 Dec 15. Arterioscler Thromb Vasc Biol. 2012. PMID: 22173226
Joint bleeds in von Willebrand disease patients have significant impact on quality of life and joint integrity: a cross-sectional study.
van Galen KPM, Sanders YV, Vojinovic U, Eikenboom J, Cnossen MH, Schutgens REG, van der Bom JG, Fijnvandraat K, Laros-Van Gorkom BAP, Meijer K, Leebeek FWG, Mauser-Bunschoten EP; WiN Study Group. van Galen KPM, et al. Among authors: schutgens reg. Haemophilia. 2015 May;21(3):e185-e192. doi: 10.1111/hae.12670. Epub 2015 Apr 9. Haemophilia. 2015. PMID: 25854528
The "OPTI-CLOT" trial. A randomised controlled trial on periOperative PharmacokineTIc-guided dosing of CLOTting factor concentrate in haemophilia A.
Hazendonk HC, van Moort I, Fijnvandraat K, Kruip MJ, Laros-van Gorkom BA, van der Meer FJ, Meijer K, Peters M, Schutgens RE, Zwaan CM, Driessens MH, Polinder S, Leebeek FW, Mathôt RA, Cnossen MH. Hazendonk HC, et al. Thromb Haemost. 2015 Aug 31;114(3):639-44. doi: 10.1160/TH14-11-0925. Epub 2015 Jun 11. Thromb Haemost. 2015. PMID: 26062822 Clinical Trial.
481 results