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Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose.
Li-Gao R, de Mutsert R, Rensen PCN, van Klinken JB, Prehn C, Adamski J, van Hylckama Vlieg A, den Heijer M, le Cessie S, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO. Li-Gao R, et al. Among authors: willems van dijk k, van klinken jb, van hylckama vlieg a. Metabolomics. 2018;14(1):13. doi: 10.1007/s11306-017-1307-7. Epub 2017 Dec 12. Metabolomics. 2018. PMID: 29249917 Free PMC article.
ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression.
Gerritsen G, Rensen PC, Kypreos KE, Zannis VI, Havekes LM, Willems van Dijk K. Gerritsen G, et al. Among authors: willems van dijk k. J Lipid Res. 2005 Jul;46(7):1466-73. doi: 10.1194/jlr.M400479-JLR200. Epub 2005 May 1. J Lipid Res. 2005. PMID: 15863838 Free article.
CETP does not affect triglyceride production or clearance in APOE*3-Leiden mice.
Bijland S, van den Berg SA, Voshol PJ, van den Hoek AM, Princen HM, Havekes LM, Rensen PC, Willems van Dijk K. Bijland S, et al. Among authors: van den hoek am, willems van dijk k, van den berg sa. J Lipid Res. 2010 Jan;51(1):97-102. doi: 10.1194/jlr.M900186-JLR200. J Lipid Res. 2010. PMID: 19564641 Free PMC article.
Perfluoroalkyl sulfonates cause alkyl chain length-dependent hepatic steatosis and hypolipidemia mainly by impairing lipoprotein production in APOE*3-Leiden CETP mice.
Bijland S, Rensen PC, Pieterman EJ, Maas AC, van der Hoorn JW, van Erk MJ, Havekes LM, Willems van Dijk K, Chang SC, Ehresman DJ, Butenhoff JL, Princen HM. Bijland S, et al. Among authors: willems van dijk k, van der hoorn jw, van erk mj. Toxicol Sci. 2011 Sep;123(1):290-303. doi: 10.1093/toxsci/kfr142. Epub 2011 Jun 24. Toxicol Sci. 2011. PMID: 21705711
Calorie restriction is a major determinant of the short-term metabolic effects of gastric bypass surgery in obese type 2 diabetic patients.
Lips MA, de Groot GH, van Klinken JB, Aarts E, Berends FJ, Janssen IM, Van Ramshorst B, Van Wagensveld BA, Swank DJ, Van Dielen F, Willems van Dijk K, Pijl H. Lips MA, et al. Among authors: van wagensveld ba, willems van dijk k, van klinken jb, van dielen f, van ramshorst b. Clin Endocrinol (Oxf). 2014 Jun;80(6):834-42. doi: 10.1111/cen.12254. Epub 2013 Jun 20. Clin Endocrinol (Oxf). 2014. PMID: 23711328
Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration.
Wang Y, Parlevliet ET, Geerling JJ, van der Tuin SJ, Zhang H, Bieghs V, Jawad AH, Shiri-Sverdlov R, Bot I, de Jager SC, Havekes LM, Romijn JA, Willems van Dijk K, Rensen PC. Wang Y, et al. Among authors: van der tuin sj, willems van dijk k. Br J Pharmacol. 2014 Feb;171(3):723-34. doi: 10.1111/bph.12490. Br J Pharmacol. 2014. PMID: 24490861 Free PMC article.
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Among authors: willems van dijk k, van den berg s. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
Genetics of the human metabolome, what is next?
Dharuri H, Demirkan A, van Klinken JB, Mook-Kanamori DO, van Duijn CM, 't Hoen PA, Willems van Dijk K. Dharuri H, et al. Among authors: van duijn cm, willems van dijk k, van klinken jb. Biochim Biophys Acta. 2014 Oct;1842(10):1923-1931. doi: 10.1016/j.bbadis.2014.05.030. Epub 2014 Jun 4. Biochim Biophys Acta. 2014. PMID: 24905732 Free article. Review.
Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.
Dharuri H, 't Hoen PA, van Klinken JB, Henneman P, Laros JF, Lips MA, El Bouazzaoui F, van Ommen GJ, Janssen I, van Ramshorst B, van Wagensveld BA, Pijl H, Willems van Dijk K, van Harmelen V. Dharuri H, et al. Among authors: van harmelen v, van wagensveld ba, willems van dijk k, van klinken jb, van ommen gj, van ramshorst b. Diabetologia. 2014 Nov;57(11):2384-92. doi: 10.1007/s00125-014-3347-0. Epub 2014 Aug 7. Diabetologia. 2014. PMID: 25099943
133 results