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Severe infections emerge from commensal bacteria by adaptive evolution.
Young BC, Wu CH, Gordon NC, Cole K, Price JR, Liu E, Sheppard AE, Perera S, Charlesworth J, Golubchik T, Iqbal Z, Bowden R, Massey RC, Paul J, Crook DW, Peto TE, Walker AS, Llewelyn MJ, Wyllie DH, Wilson DJ. Young BC, et al. Among authors: charlesworth j. Elife. 2017 Dec 19;6:e30637. doi: 10.7554/eLife.30637. Elife. 2017. PMID: 29256859 Free PMC article.
Antimicrobial resistance determinants are associated with Staphylococcus aureus bacteraemia and adaptation to the healthcare environment: a bacterial genome-wide association study.
Young BC, Wu CH, Charlesworth J, Earle S, Price JR, Gordon NC, Cole K, Dunn L, Liu E, Oakley S, Godwin H, Fung R, Miller R, Knox K, Votintseva A, Quan TP, Tilley R, Scarborough M, Crook DW, Peto TE, Walker AS, Llewelyn MJ, Wilson DJ. Young BC, et al. Among authors: charlesworth j. Microb Genom. 2021 Nov;7(11):000700. doi: 10.1099/mgen.0.000700. Microb Genom. 2021. PMID: 34812717 Free PMC article.
Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus.
Everitt RG, Didelot X, Batty EM, Miller RR, Knox K, Young BC, Bowden R, Auton A, Votintseva A, Larner-Svensson H, Charlesworth J, Golubchik T, Ip CL, Godwin H, Fung R, Peto TE, Walker AS, Crook DW, Wilson DJ. Everitt RG, et al. Among authors: charlesworth j. Nat Commun. 2014 May 23;5:3956. doi: 10.1038/ncomms4956. Nat Commun. 2014. PMID: 24853639 Free PMC article.
Identifying lineage effects when controlling for population structure improves power in bacterial association studies.
Earle SG, Wu CH, Charlesworth J, Stoesser N, Gordon NC, Walker TM, Spencer CCA, Iqbal Z, Clifton DA, Hopkins KL, Woodford N, Smith EG, Ismail N, Llewelyn MJ, Peto TE, Crook DW, McVean G, Walker AS, Wilson DJ. Earle SG, et al. Among authors: charlesworth j. Nat Microbiol. 2016 Apr 4;1:16041. doi: 10.1038/nmicrobiol.2016.41. Nat Microbiol. 2016. PMID: 27572646 Free PMC article.
The rate of adaptive evolution in enteric bacteria.
Charlesworth J, Eyre-Walker A. Charlesworth J, et al. Mol Biol Evol. 2006 Jul;23(7):1348-56. doi: 10.1093/molbev/msk025. Epub 2006 Apr 18. Mol Biol Evol. 2006. PMID: 16621913
Wolbachia, Cardinium and climate: an analysis of global data.
Charlesworth J, Weinert LA, Araujo EV Jr, Welch JJ. Charlesworth J, et al. Biol Lett. 2019 Aug 30;15(8):20190273. doi: 10.1098/rsbl.2019.0273. Epub 2019 Aug 21. Biol Lett. 2019. PMID: 31432763 Free PMC article.
289 results