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A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Böiers C, Richardson SE, Laycock E, Zriwil A, Turati VA, Brown J, Wray JP, Wang D, James C, Herrero J, Sitnicka E, Karlsson S, Smith AJH, Jacobsen SEW, Enver T. Böiers C, et al. Among authors: james c. Dev Cell. 2018 Feb 5;44(3):362-377.e7. doi: 10.1016/j.devcel.2017.12.005. Epub 2017 Dec 28. Dev Cell. 2018. PMID: 29290585 Free PMC article.
Generation and trapping of a mesoderm biased state of human pluripotency.
Stavish D, Böiers C, Price C, Frith TJR, Halliwell J, Saldaña-Guerrero I, Wray J, Brown J, Carr J, James C, Barbaric I, Andrews PW, Enver T. Stavish D, et al. Among authors: james c. Nat Commun. 2020 Oct 5;11(1):4989. doi: 10.1038/s41467-020-18727-8. Nat Commun. 2020. PMID: 33020476 Free PMC article.
Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes.
Marshall A, Kasturiarachchi J, Datta P, Guo Y, Deltcheva E, James C, Brown J, May G, Anandagoda N, Jackson I, Howard JK, Ghazaly E, Brooks S, Khwaja A, Araki M, Araki K, Linch D, Lord GM, Enver T, Nimmo R. Marshall A, et al. Among authors: james c. Sci Rep. 2020 Nov 10;10(1):19390. doi: 10.1038/s41598-020-76218-8. Sci Rep. 2020. PMID: 33173219 Free PMC article.
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.
Turati VA, Guerra-Assunção JA, Potter NE, Gupta R, Ecker S, Daneviciute A, Tarabichi M, Webster AP, Ding C, May G, James C, Brown J, Conde L, Russell LJ, Ancliff P, Inglott S, Cazzaniga G, Biondi A, Hall GW, Lynch M, Hubank M, Macaulay I, Beck S, Van Loo P, Jacobsen SE, Greaves M, Herrero J, Enver T. Turati VA, et al. Among authors: james c. Nat Cancer. 2021 Aug;2(8):835-852. doi: 10.1038/s43018-021-00219-3. Epub 2021 Jul 5. Nat Cancer. 2021. PMID: 34734190 Free PMC article.
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Azzoni E, Frontera V, Anselmi G, Rode C, James C, Deltcheva EM, Demian AS, Brown J, Barone C, Patelli A, Harman JR, Nicholls M, Conway SJ, Morrissey E, Jacobsen SEW, Sparrow DB, Harris AL, Enver T, de Bruijn MFTR. Azzoni E, et al. Among authors: james c. Cell Rep. 2021 Dec 14;37(11):110103. doi: 10.1016/j.celrep.2021.110103. Cell Rep. 2021. PMID: 34910918 Free PMC article.
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
Geron I, Savino AM, Fishman H, Tal N, Brown J, Turati VA, James C, Sarno J, Hameiri-Grossman M, Lee YN, Rein A, Maniriho H, Birger Y, Zemlyansky A, Muler I, Davis KL, Marcu-Malina V, Mattson N, Parnas O, Wagener R, Fischer U, Barata JT, Jamieson CHM, Müschen M, Chen CW, Borkhardt A, Kirsch IR, Nagler A, Enver T, Izraeli S. Geron I, et al. Among authors: james c. Nat Commun. 2022 Feb 3;13(1):659. doi: 10.1038/s41467-022-28218-7. Nat Commun. 2022. PMID: 35115489 Free PMC article.
Author Correction: Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes.
Marshall A, Kasturiarachchi J, Datta P, Guo Y, Deltcheva E, James C, Brown J, May G, Anandagoda N, Jackson I, Howard JK, Ghazaly E, Brooks S, Khwaja A, Araki M, Araki K, Linch D, Lord GM, Enver T, Nimmo R. Marshall A, et al. Among authors: james c. Sci Rep. 2021 Mar 23;11(1):6974. doi: 10.1038/s41598-021-84578-y. Sci Rep. 2021. PMID: 33753768 Free PMC article. No abstract available.
MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function.
Roberts LB, Jowett GM, Read E, Zabinski T, Berkachy R, Selkirk ME, Jackson I, Niazi U, Anandagoda N, Araki M, Araki K, Kasturiarachchi J, James C, Enver T, Nimmo R, Reis R, Howard JK, Neves JF, Lord GM. Roberts LB, et al. Among authors: james c. J Immunol. 2021 Jun 1;206(11):2725-2739. doi: 10.4049/jimmunol.2000647. Epub 2021 May 21. J Immunol. 2021. PMID: 34021046 Free PMC article.
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Househam J, Heide T, Cresswell GD, Spiteri I, Kimberley C, Zapata L, Lynn C, James C, Mossner M, Fernandez-Mateos J, Vinceti A, Baker AM, Gabbutt C, Berner A, Schmidt M, Chen B, Lakatos E, Gunasri V, Nichol D, Costa H, Mitchinson M, Ramazzotti D, Werner B, Iorio F, Jansen M, Caravagna G, Barnes CP, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Sottoriva A, Graham TA. Househam J, et al. Among authors: james c. Nature. 2022 Nov;611(7937):744-753. doi: 10.1038/s41586-022-05311-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289336 Free PMC article.
2,444 results