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Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.
Carrelha J, Meng Y, Kettyle LM, Luis TC, Norfo R, Alcolea V, Boukarabila H, Grasso F, Gambardella A, Grover A, Högstrand K, Lord AM, Sanjuan-Pla A, Woll PS, Nerlov C, Jacobsen SEW. Carrelha J, et al. Among authors: kettyle lm. Nature. 2018 Feb 1;554(7690):106-111. doi: 10.1038/nature25455. Epub 2018 Jan 3. Nature. 2018. PMID: 29298288
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.
Di Genua C, Norfo R, Rodriguez-Meira A, Wen WX, Drissen R, Booth CAG, Povinelli B, Repapi E, Gray N, Carrelha J, Kettyle LM, Jamieson L, Neo WH, Thongjuea S, Nerlov C, Mead AJ. Di Genua C, et al. Among authors: kettyle lm. Haematologica. 2019 Nov;104(11):2215-2224. doi: 10.3324/haematol.2018.205351. Epub 2019 Apr 11. Haematologica. 2019. PMID: 30975913 Free PMC article.
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.
Wojtowicz EE, Mistry JJ, Uzun V, Hellmich C, Scoones A, Chin DW, Kettyle LM, Grasso F, Lord AM, Wright DJ, Etherington GJ, Woll PS, Belderbos ME, Bowles KM, Nerlov C, Haerty W, Bystrykh LV, Jacobsen SEW, Rushworth SA, Macaulay IC. Wojtowicz EE, et al. Among authors: kettyle lm. Genome Biol. 2023 Jun 27;24(1):152. doi: 10.1186/s13059-023-02976-z. Genome Biol. 2023. PMID: 37370129 Free PMC article.
Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells.
Belander Strålin K, Carrelha J, Winroth A, Ziegenhain C, Hagemann-Jensen M, Kettyle LM, Hillen A, Högstrand K, Markljung E, Grasso F, Seki M, Mazzi S, Meng Y, Wu B, Chari E, Lehander M, Sandberg R, Woll PS, Jacobsen SEW. Belander Strålin K, et al. Among authors: kettyle lm. Cell Res. 2023 Nov;33(11):883-886. doi: 10.1038/s41422-023-00866-4. Epub 2023 Sep 6. Cell Res. 2023. PMID: 37674010 Free PMC article. No abstract available.
c-Met inhibition in a HOXA9/Meis1 model of CN-AML.
Mulgrew NM, Kettyle LM, Ramsey JM, Cull S, Smyth LJ, Mervyn DM, Bijl JJ, Thompson A. Mulgrew NM, et al. Among authors: kettyle lm. Dev Dyn. 2014 Jan;243(1):172-81. doi: 10.1002/dvdy.24070. Epub 2013 Dec 4. Dev Dyn. 2014. PMID: 24307265 Free article.
15 results