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Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases.
FitzGerald LM, Zhao S, Leonardson A, Geybels MS, Kolb S, Lin DW, Wright JL, Eeles R, Kote-Jarai Z, Govindasami K, Giles GG, Southey MC, Schleutker J, Tammela TL, Sipeky C, Penney KL, Stampfer MJ, Gronberg H, Wiklund F, Stattin P, Hugosson J, Karyadi DM, Ostrander EA, Feng Z, Stanford JL. FitzGerald LM, et al. Prostate Cancer Prostatic Dis. 2018 Jun;21(2):228-237. doi: 10.1038/s41391-017-0029-2. Epub 2018 Jan 3. Prostate Cancer Prostatic Dis. 2018. PMID: 29298992 Free PMC article.
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.
Edwards SM, Kote-Jarai Z, Meitz J, Hamoudi R, Hope Q, Osin P, Jackson R, Southgate C, Singh R, Falconer A, Dearnaley DP, Ardern-Jones A, Murkin A, Dowe A, Kelly J, Williams S, Oram R, Stevens M, Teare DM, Ponder BA, Gayther SA, Easton DF, Eeles RA; Cancer Research UK/Bristish Prostate Group UK Familial Prostate Cancer Study Collaborators; British Association of Urological Surgeons Section of Oncology. Edwards SM, et al. Am J Hum Genet. 2003 Jan;72(1):1-12. doi: 10.1086/345310. Epub 2002 Dec 9. Am J Hum Genet. 2003. PMID: 12474142 Free PMC article.
Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer.
Kote-Jarai Z, Durocher F, Edwards SM, Hamoudi R, Jackson RA, Ardern-Jones A, Murkin A, Dearnaley DP, Kirby R, Houlston R, Easton DF, Eeles R; CRC/BPG UK Familial Prostrate Cancer Collaborators. Kote-Jarai Z, et al. Prostate Cancer Prostatic Dis. 2002;5(3):189-92. doi: 10.1038/sj.pcan.4500569. Prostate Cancer Prostatic Dis. 2002. PMID: 12496980
High risk genes predisposing to prostate cancer development-do they exist?
Singh R, Eeles RA, Durocher F, Simard J, Edwards S, Badzioch M, Kote-Jarai Z, Teare D, Ford D, Dearnaley D, Ardern-Jones A, Murkin A, Dowe A, Shearer R, Kelly J, Labrie F, Easton D, Narod SA, Tonin PN, Foulkes WD. Singh R, et al. Prostate Cancer Prostatic Dis. 2000 Dec;3(4):241-247. doi: 10.1038/sj.pcan.4500478. Prostate Cancer Prostatic Dis. 2000. PMID: 12497071
292 results