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A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.
Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q. Panganiban RA, et al. Among authors: randell sh. J Allergy Clin Immunol. 2018 Nov;142(5):1469-1478.e2. doi: 10.1016/j.jaci.2017.11.040. Epub 2018 Jan 9. J Allergy Clin Immunol. 2018. PMID: 29330013 Free PMC article.
Unjamming and cell shape in the asthmatic airway epithelium.
Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R Jr, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Park JA, et al. Among authors: randell sh. Nat Mater. 2015 Oct;14(10):1040-8. doi: 10.1038/nmat4357. Epub 2015 Aug 3. Nat Mater. 2015. PMID: 26237129 Free PMC article.
Compressive Stress Causes an Unjamming Transition and an Epithelial-Mesenchymal Transition in the Airway Epithelium in Asthma.
Park JA, Mitchel JA, Qazvini NT, Kim JH, Park CY, Butler JP, Israel E, Randell SH, Shore SA, Drazen JM, Fredberg JJ. Park JA, et al. Among authors: randell sh. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1(Suppl 1):S102. doi: 10.1513/AnnalsATS.201506-382MG. Ann Am Thorac Soc. 2016. PMID: 27027941 Free PMC article. No abstract available.
Mechanical forces induce an asthma gene signature in healthy airway epithelial cells.
Kılıç A, Ameli A, Park JA, Kho AT, Tantisira K, Santolini M, Cheng F, Mitchel JA, McGill M, O'Sullivan MJ, De Marzio M, Sharma A, Randell SH, Drazen JM, Fredberg JJ, Weiss ST. Kılıç A, et al. Among authors: randell sh. Sci Rep. 2020 Jan 22;10(1):966. doi: 10.1038/s41598-020-57755-8. Sci Rep. 2020. PMID: 31969610 Free PMC article.
Well-differentiated human airway epithelial cell cultures.
Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH. Fulcher ML, et al. Among authors: randell sh. Methods Mol Med. 2005;107:183-206. doi: 10.1385/1-59259-861-7:183. Methods Mol Med. 2005. PMID: 15492373 No abstract available.
238 results