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Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis.
Kochi Y, Kamatani Y, Kondo Y, Suzuki A, Kawakami E, Hiwa R, Momozawa Y, Fujimoto M, Jinnin M, Tanaka Y, Kanda T, Cooper RG, Chinoy H, Rothwell S, Lamb JA, Vencovský J, Mann H, Ohmura K, Myouzen K, Ishigaki K, Nakashima R, Hosono Y, Tsuboi H, Kawasumi H, Iwasaki Y, Kajiyama H, Horita T, Ogawa-Momohara M, Takamura A, Tsunoda S, Shimizu J, Fujio K, Amano H, Mimori A, Kawakami A, Umehara H, Takeuchi T, Sano H, Muro Y, Atsumi T, Mimura T, Kawaguchi Y, Mimori T, Takahashi A, Kubo M, Kohsaka H, Sumida T, Yamamoto K. Kochi Y, et al. Among authors: hiwa r. Ann Rheum Dis. 2018 Apr;77(4):602-611. doi: 10.1136/annrheumdis-2017-212149. Epub 2018 Jan 13. Ann Rheum Dis. 2018. PMID: 29331962
Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility.
Jin H, Arase N, Hirayasu K, Kohyama M, Suenaga T, Saito F, Tanimura K, Matsuoka S, Ebina K, Shi K, Toyama-Sorimachi N, Yasuda S, Horita T, Hiwa R, Takasugi K, Ohmura K, Yoshikawa H, Saito T, Atsumi T, Sasazuki T, Katayama I, Lanier LL, Arase H. Jin H, et al. Among authors: hiwa r. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3787-92. doi: 10.1073/pnas.1401105111. Epub 2014 Feb 24. Proc Natl Acad Sci U S A. 2014. PMID: 24567378 Free PMC article.
Only rheumatoid factor-positive subset of anti-citrullinated peptide/protein antibody-negative rheumatoid arthritis may seroconvert to anti-citrullinated peptide/protein antibody-positive.
Hiwa R, Ohmura K, Nakabo S, Terao C, Murakami K, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Hashimoto M, Furu M, Ito H, Fujii T, Mimori T. Hiwa R, et al. Int J Rheum Dis. 2017 Jun;20(6):731-736. doi: 10.1111/1756-185X.13000. Epub 2017 Feb 15. Int J Rheum Dis. 2017. PMID: 28198158
HLA-DRB1 Analysis Identified a Genetically Unique Subset within Rheumatoid Arthritis and Distinct Genetic Background of Rheumatoid Factor Levels from Anticyclic Citrullinated Peptide Antibodies.
Hiwa R, Ikari K, Ohmura K, Nakabo S, Matsuo K, Saji H, Yurugi K, Miura Y, Maekawa T, Taniguchi A, Yamanaka H, Matsuda F, Mimori T, Terao C. Hiwa R, et al. J Rheumatol. 2018 Apr;45(4):470-480. doi: 10.3899/jrheum.170363. Epub 2018 Feb 1. J Rheumatol. 2018. PMID: 29419463
Genetic architecture underlying IgG-RF production is distinct from that of IgM-RF.
Yaku A, Ishikawa Y, Iwasaki T, Hiwa R, Matsuo K, Saji H, Yurugi K, Miura Y, Furu M, Ito H, Fujii T, Maekawa T, Hashimoto M, Ohmura K, Mimori T, Terao C. Yaku A, et al. Among authors: hiwa r. Rheumatology (Oxford). 2023 May 2;62(5):2015-2020. doi: 10.1093/rheumatology/keac593. Rheumatology (Oxford). 2023. PMID: 36250908
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