Growcott E - Search Results

1

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

Reck F, Bermingham A, Blais J, Capka V, Cariaga T, Casarez A, Colvin R, Dean CR, Fekete A, Gong W, Growcott E, Guo H, Jones AK, Li C, Li F, Lin X, Lindvall M, Lopez S, McKenney D, Metzger L, Moser HE, Prathapam R, Rasper D, Rudewicz P, Sethuraman V, Shen X, Shaul J, Simmons RL, Tashiro K, Tang D, Tjandra M, Turner N, Uehara T, Vitt C, Whitebread S, Yifru A, Zang X, Zhu Q. Reck F, et al. Among authors: growcott e. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. doi: 10.1016/j.bmcl.2018.01.006. Epub 2018 Jan 4. Bioorg Med Chem Lett. 2018. PMID: 29336873

2

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

Growcott EJ, Cariaga TA, Morris L, Zang X, Lopez S, Ansaldi DA, Gold J, Gamboa L, Roth T, Simmons RL, Osborne CS. Growcott EJ, et al. J Antimicrob Chemother. 2019 Jan 1;74(1):108-116. doi: 10.1093/jac/dky404. J Antimicrob Chemother. 2019. PMID: 30325447

3

Efficacy of piperacillin in combination with novel β-lactamase inhibitor IID572 against β-lactamase-producing strains of Enterobacteriaceae and Staphylococcus aureus in murine neutropenic thigh infection models.

Growcott EJ, Gamboa L, Roth T, Lopez S, Osborne CS. Growcott EJ, et al. J Antimicrob Chemother. 2020 Jun 1;75(6):1530-1536. doi: 10.1093/jac/dkaa026. J Antimicrob Chemother. 2020. PMID: 32108878

4

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

Growcott EJ, Cariaga TA, Morris L, Zang X, Lopez S, Ansaldi DA, Gold J, Gamboa L, Roth T, Simmons RL, Osborne CS. Growcott EJ, et al. J Antimicrob Chemother. 2019 Jan 1;74(1):280. doi: 10.1093/jac/dky478. J Antimicrob Chemother. 2019. PMID: 30412250 No abstract available.

5

In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection.

Weiss WJ, Pulse ME, Nguyen P, Growcott EJ. Weiss WJ, et al. Among authors: growcott ej. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02214-18. doi: 10.1128/AAC.02214-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30642927 Free PMC article.

6

The effect of P38 MAP kinase inhibition in a mouse model of influenza.

Growcott EJ, Bamba D, Galarneau JR, Leonard VHJ, Schul W, Stein D, Osborne CS. Growcott EJ, et al. J Med Microbiol. 2018 Mar;67(3):452-462. doi: 10.1099/jmm.0.000684. Epub 2018 Jan 24. J Med Microbiol. 2018. PMID: 29458547

7

Characterisation of a refined rat model of respiratory infection with Pseudomonas aeruginosa and the effect of ciprofloxacin.

Growcott EJ, Coulthard A, Amison R, Hardaker EL, Saxena V, Malt L, Jones P, Grevot A, Poll C, Osborne C, Banner KH. Growcott EJ, et al. J Cyst Fibros. 2011 May;10(3):166-74. doi: 10.1016/j.jcf.2010.12.007. Epub 2011 Jan 17. J Cyst Fibros. 2011. PMID: 21247812 Free article.

8

A Cyclic Phosphoramidate Prodrug of 2'-Deoxy-2'-Fluoro-2'-C-Methylguanosine for the Treatment of Dengue Virus Infection.

Karuna R, Yokokawa F, Wang K, Zhang J, Xu H, Wang G, Ding M, Chan WL, Abdul Ghafar N, Leonardi A, Seh CC, Seah PG, Liu W, Srinivasa RPS, Lim SP, Lakshminarayana SB, Growcott E, Babu S, Fenaux M, Zhong W, Gu F, Shi PY, Blasco F, Chen YL. Karuna R, et al. Among authors: growcott e. Antimicrob Agents Chemother. 2020 Nov 17;64(12):e00654-20. doi: 10.1128/AAC.00654-20. Print 2020 Nov 17. Antimicrob Agents Chemother. 2020. PMID: 32958712 Free PMC article.

9

The role of airway mucus and diseased pulmonary epithelium on the absorption of inhaled antibodies.

Ledo AM, Dimke T, Tschantz WR, Rowlands D, Growcott E. Ledo AM, et al. Among authors: growcott e. Int J Pharm. 2023 Nov 25;647:123519. doi: 10.1016/j.ijpharm.2023.123519. Epub 2023 Oct 16. Int J Pharm. 2023. PMID: 37852310

10

Aerosol technology to mimic dry powder inhalation in vitro using pulmonary cell models.

Ledo AM, Thibodeaux S, Duong L, Altinoglu E, Dimke T, Shaw D, Rowlands D, Growcott E. Ledo AM, et al. Among authors: growcott e. Eur J Pharm Biopharm. 2023 Jul;188:201-216. doi: 10.1016/j.ejpb.2023.05.009. Epub 2023 May 15. Eur J Pharm Biopharm. 2023. PMID: 37196872

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