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Page 1
Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours.
Izquierdo E, Yuan L, George S, Hubank M, Jones C, Proszek P, Shipley J, Gatz SA, Stinson C, Moore AS, Clifford SC, Hicks D, Lindsey JC, Hill RM, Jacques TS, Chalker J, Thway K, O'Connor S, Marshall L, Moreno L, Pearson A, Chesler L, Walker BA, De Castro DG. Izquierdo E, et al. Among authors: de castro dg. Oncotarget. 2017 Dec 6;8(67):112036-112050. doi: 10.18632/oncotarget.23000. eCollection 2017 Dec 19. Oncotarget. 2017. PMID: 29340109 Free PMC article.
Genomic landscape of platinum resistant and sensitive testicular cancers.
Loveday C, Litchfield K, Proszek PZ, Cornish AJ, Santo F, Levy M, Macintyre G, Holryod A, Broderick P, Dudakia D, Benton B, Bakir MA, Hiley C, Grist E, Swanton C, Huddart R, Powles T, Chowdhury S, Shipley J, O'Connor S, Brenton JD, Reid A, de Castro DG, Houlston RS, Turnbull C. Loveday C, et al. Among authors: de castro dg. Nat Commun. 2020 May 4;11(1):2189. doi: 10.1038/s41467-020-15768-x. Nat Commun. 2020. PMID: 32366847 Free PMC article.
Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial.
Kapp JR, Diss T, Spicer J, Gandy M, Schrijver I, Jennings LJ, Li MM, Tsongalis GJ, de Castro DG, Bridge JA, Wallace A, Deignan JL, Hing S, Butler R, Verghese E, Latham GJ, Hamoudi RA. Kapp JR, et al. Among authors: de castro dg. J Clin Pathol. 2015 Feb;68(2):111-8. doi: 10.1136/jclinpath-2014-202644. Epub 2014 Nov 27. J Clin Pathol. 2015. PMID: 25430497 Free PMC article.
An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice.
Ellison G, Ahdesmäki M, Luke S, Waring PM, Wallace A, Wright R, Röthlisberger B, Ludin K, Merkelbach-Bruse S, Heydt C, Ligtenberg MJL, Mensenkamp AR, de Castro DG, Jones T, Vivancos A, Kondrashova O, Pauwels P, Weyn C, Hahnen E, Hauke J, Soong R, Lai Z, Dougherty B, Carr TH, Johnson J, Mills J, Barrett JC. Ellison G, et al. Among authors: de castro dg. Hum Mutat. 2018 Mar;39(3):394-405. doi: 10.1002/humu.23375. Epub 2017 Dec 28. Hum Mutat. 2018. PMID: 29215764 Free PMC article.
KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer.
Sclafani F, Chau I, Cunningham D, Hahne JC, Vlachogiannis G, Eltahir Z, Lampis A, Braconi C, Kalaitzaki E, De Castro DG, Wotherspoon A, Capdevila J, Glimelius B, Tarazona N, Begum R, Lote H, Hulkki Wilson S, Mentrasti G, Brown G, Tait D, Oates J, Valeri N. Sclafani F, et al. Among authors: de castro dg. Sci Rep. 2018 Jan 23;8(1):1445. doi: 10.1038/s41598-018-19212-5. Sci Rep. 2018. PMID: 29362371 Free PMC article. Clinical Trial.
Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.
Lawler M, Alsina D, Adams RA, Anderson AS, Brown G, Fearnhead NS, Fenwick SW, Halloran SP, Hochhauser D, Hull MA, Koelzer VH, McNair AGK, Monahan KJ, Näthke I, Norton C, Novelli MR, Steele RJC, Thomas AL, Wilde LM, Wilson RH, Tomlinson I; Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative. Lawler M, et al. Gut. 2018 Jan;67(1):179-193. doi: 10.1136/gutjnl-2017-315333. Gut. 2018. PMID: 29233930 Free PMC article. Review.
44 results