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MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Howson LJ, Napolitani G, Shepherd D, Ghadbane H, Kurupati P, Preciado-Llanes L, Rei M, Dobinson HC, Gibani MM, Teng KWW, Newell EW, Veerapen N, Besra GS, Pollard AJ, Cerundolo V. Howson LJ, et al. Among authors: napolitani g. Nat Commun. 2018 Jan 17;9(1):253. doi: 10.1038/s41467-017-02540-x. Nat Commun. 2018. PMID: 29343684 Free PMC article.
Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.
Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V. Napolitani G, et al. Nat Immunol. 2018 Jul;19(7):742-754. doi: 10.1038/s41590-018-0133-z. Epub 2018 Jun 20. Nat Immunol. 2018. PMID: 29925993
Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.
Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, Aichinger MC, Napolitani G, Qi X, van der Merwe PA, Wojno J, Veerapen N, Cox LR, Besra GS, Yuan W, Cresswell P, Cerundolo V. Salio M, et al. Among authors: napolitani g. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4753-61. doi: 10.1073/pnas.1310050110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248359 Free PMC article.
Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.
Salio M, Gasser O, Gonzalez-Lopez C, Martens A, Veerapen N, Gileadi U, Verter JG, Napolitani G, Anderson R, Painter G, Besra GS, Hermans IF, Cerundolo V. Salio M, et al. Among authors: napolitani g. J Immunol. 2017 Oct 15;199(8):2631-2638. doi: 10.4049/jimmunol.1700615. Epub 2017 Sep 6. J Immunol. 2017. PMID: 28877992 Free PMC article.
Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.
Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V. Napolitani G, et al. Nat Immunol. 2019 Apr;20(4):514. doi: 10.1038/s41590-019-0357-6. Nat Immunol. 2019. PMID: 30862955
Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.
Preciado-Llanes L, Aulicino A, Canals R, Moynihan PJ, Zhu X, Jambo N, Nyirenda TS, Kadwala I, Sousa Gerós A, Owen SV, Jambo KC, Kumwenda B, Veerapen N, Besra GS, Gordon MA, Hinton JCD, Napolitani G, Salio M, Simmons A. Preciado-Llanes L, et al. Among authors: napolitani g. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20717-20728. doi: 10.1073/pnas.2007472117. Epub 2020 Aug 11. Proc Natl Acad Sci U S A. 2020. PMID: 32788367 Free PMC article.
Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model.
Gibani MM, Jin C, Shrestha S, Moore M, Norman L, Voysey M, Jones E, Blackwell L, Thomaides-Brears H, Hill J, Blohmke CJ, Dobinson HC, Baker P, Jones C, Campbell D, Mujadidi YF, Plested E, Preciado-Llanes L, Napolitani G, Simmons A, Gordon MA, Angus B, Darton TC, Cerundulo V, Pollard AJ. Gibani MM, et al. Among authors: napolitani g. PLoS Negl Trop Dis. 2020 Oct 20;14(10):e0008783. doi: 10.1371/journal.pntd.0008783. eCollection 2020 Oct. PLoS Negl Trop Dis. 2020. PMID: 33079959 Free PMC article. Clinical Trial.
Human autoreactive T cells recognize CD1b and phospholipids.
Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB. Van Rhijn I, et al. Among authors: napolitani g. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):380-5. doi: 10.1073/pnas.1520947112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2016. PMID: 26621732 Free PMC article.
42 results